Results 91 to 100 of about 2,625,265 (373)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A FORMAL CONCEPT OF CULTURE IN THE CLASSIFICATION OF ALFRED L. KROEBER AND CLYDE KLUCKHOHN [PDF]

, 2016
The objective of this article is to analyse definitions of culture gathered by Alfred L. Kroeber and Clyde Kluckhohn and published in Culture. A Critical Review of Concepts and Definitions in 1952.
Robert, Boroch
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Evaluation of Honoring the Gift of Heart Health: The Strong Heart Study

Journal of Primary Care & Community Health
Due to the higher rates of cardiovascular disease (CVD), the “Honoring the Gift of Heart Health” CVD risk factor educational program was developed specifically for American Indian communities.
Jessica A. Reese, Megan Eisele, Aimee Jones, Tauqeer Ali, Elisa T. Lee, Kerstin M. Reinschmidt, Ying Zhang   +6 more
doaj   +1 more source

Art, Artifact, Archive: African American Experiences in the Nineteenth Century

, 2015
Angelo Scarlato’s extraordinary and vast collection of art and artifacts related to the Civil War, and specifically to the Battle of Gettysburg, the United States Colored Troops, slavery and the African American struggle for emancipation, citizenship and
Brennan, Diane, Conley, Maura B., Conner, Abigail B., Conte, Nicole A., Egan, Shannon, Perez-Zetune, Victoria, Roedner, Lauren H., Rose, Savannah, Sawyer, Kaylyn L., Wood, Caroline M., Yeoh, Zoe C.   +10 more
core  

Analysis of the 19th Century Historic Archaeological Material Culture Remains from the Browning Site in Smith County, Texas [PDF]

, 2011
The Browning site (41SM195A) is located on a 3800 m2 alluvial terrace that overlooks the Auburn Creek floodplain in eastern Smith County, Texas. This setting is near the headwaters of a stream system in the Harris Creek drainage; Harris Creek meets the ...
Perttula, Timothy K., Walters, Mark
core   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

A survey and comparison of luxury item ownership in the eighteenth century Dutch Cape Colony [PDF]

What we know about the material culture of eighteenth century Cape Colony settlers is mostly limited to qualitative evidence found in official documents, letters, travel accounts and other correspondence.
Johan Fourie, Jolandi Uys
core  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source