Results 31 to 40 of about 20,932,082 (304)
Inter-American Development Bank Sustainability Report 2016 [PDF]
, 2017 This report highlights the Inter-American Development Bank\u27s sustainability performance in 2016, both in the operations it finances and at its own facilities.
Inter-American Development Bank
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
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The Nuclear Winter of Our Discontent: Soviet Animated Adaptations of American Science Fiction in the 1980s [PDF]
Литература двух АмерикThe article examines three mid-1980s Soviet animated films, based on American science fiction short stories: “There Will Come Soft Rains” (Ray Bradbury, dir. by Nazim Tulyakhodzhaev, 1984), “Contract” (Robert Silverberg, dir.
Nina A. Moroz
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The concept of culture in American anthropology [PDF]
, 1994 This dissertation is a collection of essays on the concept of culture in American cultural anthropology. Culture has been a key concept in American anthropology but anthropologists have recently been criticised for representing culture as too coherent ...
Arnason, Arnar
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
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Miranda: Revue Pluridisciplinaire du Monde Anglophone, 2017 This paper focuses upon intertextuality in Nabokov’s Lolita, but not through literary allusion. Instead, this study analyzes the way the author integrates non-literary material taken from post-World War 2 American mass culture into the textual fabric ...
Marie Bouchet
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
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, 1966 Letter from Curator, V & R Registry, American Type Culture Collection to Members of the Viral and Rickettsial Registry Committee dated 1966-04-19.Sabin Collection Fair Use ...
Curator, V & R Registry, American Type Culture Collection
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