Results 81 to 90 of about 1,943,131 (350)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Molecular Oncology, EarlyView.In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa +14 more
wiley +1 more source
Traditions in Transition: Basques in America [PDF]
, 2009 The Basque Museum & Cultural Center’s newest corridor exhibit, Traditions in Transition: Basques in America, is an interpretive exhibit based primarily on material culture artifacts, photographs and literature.
Peterson, Alissa
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The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Molecular Oncology, EarlyView.Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
Acervo, 2018 Regina A. Root (raroot@wm.edu) is Professor of Hispanic Studies at William & Mary, the historic university in Williamsburg, Virginia. She is an international expert known for her work on fashion, textiles, and Latin American cultural production.
Maria do Carmo Rainho +1 more
doaj
“Colonial Problems, Transnational American Studies” [PDF]
, 2019 Excerpt from After American Studies: Rethinking Legacies of Transnational ...
Herlihy-Mera, Jeffrey
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
A FORMAL CONCEPT OF CULTURE IN THE CLASSIFICATION OF ALFRED L. KROEBER AND CLYDE KLUCKHOHN [PDF]
, 2016 The objective of this article is to analyse definitions of culture gathered by Alfred L. Kroeber and Clyde Kluckhohn and published in Culture. A Critical Review of Concepts and Definitions in 1952.
Robert, Boroch
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Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Steps towards operationalizing an evolutionary archaeological definition of culture [PDF]
, 2011 This paper will examine the definition of archaeological cultures/techno-complexes from an evolutionary perspective, in which culture is defined as a system of social information transmission.
Riede, F
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