Results 31 to 40 of about 3,129,705 (345)

Historical Consciousness and Transnational American Studies

open access: yesJournal of Transnational American Studies, 2012
Editors' Note for JTAS 4 ...
Chris Suh, Greg Robinson
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Studies of American plants -- XXII

open access: yesPhytologia., 1987
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Forum: Digitization, Digital Humanities, and American Studies

open access: yes, 2023
Digitization and the digital humanities (DH) continue to shape the field of American studies. This forum brings together ten international scholars who assess where we as (German) Americanists stand on digital scholarship, (inter)disciplinarity, data ...
Horn, Katrin   +11 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Asian American Crossroads Lecture Series Spring 2020 Save the Dates

open access: yes, 2020
This flyer promotes the Center for Asian American Studies' Asian American Crossroads Lecturer Series for Spring 2020.Asian American ...
Center for Asian American Studies
core   +1 more source

Contributors

open access: yesAmerican Studies in Scandinavia, 2021
American Studies in Scandinavia
doaj   +3 more sources

American Studies in Scandinavia – Special issue on the Arctic

open access: yesAmerican Studies in Scandinavia, 2021
American Studies in Scandinavia
doaj   +1 more source

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