Studies of American plants -- XXII
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
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Administration and Governance in a Compound Republic: Martha Derthick’s Contributions to the Study of American Federalism [PDF]
Tim Conlan
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We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
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Identity Construction in Website News Discourse: A Corpus-assisted Comparative Study of Top 10 American and Chinese Banking Corporations [PDF]
Yong Qin
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Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
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Philippine Bibliography I. An Annotated Preliminary Bibliography of Philippine Bibliographies (Since 1900). By Charles O. Houston Jr. Manila: The University of Manila, 1960. 69. Errata sheet and index insert. $2.50. - Philippine Studies: The Poor Relation in American Scholarship. By Charles O. Houston Jr. Manila: Privately printed by the author, 1957 [1960]. 20. $1.25. [PDF]
Donn V. Hart
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Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source

