Results 111 to 120 of about 540,321 (312)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Can measles be eradicated globally?

Bulletin of the World Health Organization
Measles is one of the most infectious diseases. Before measles vaccine was introduced, nearly everyone contracted the disease at some point in childhood.
Ciro A. de Quadros
doaj   +1 more source

A new species of Ribautiella (Myriapoda, Symphyla, Scolopendrellidae) from an Amazonian black-water inundation forest and notes on its natural history and ecology

, 1984
Ribautiella amazonica is described from a black-water inundation forest near Manaus, Brazil. The genus is recorded for the first time for the Americas. R. amazonica was predominantly collected from the forest soil, mainly between 7 and 14 cm depth and is
Adis, J., Scheller, U.
core  

Trade and the Americas [PDF]

, 2003
CRS ReportCRSTradeAmericas12Sept03.pdf: 220 downloads, before Oct.
Ahearn, Raymond J.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Síndrome de burnout y su relación con la inteligencia emocional en estudiantes de enfermería

Sanus
Introducción: El síndrome de burnout, es una condición caracterizada por agotamiento emocional, despersonalización y reducida realización personal y ha surgido como una preocupación significativa en el ámbito de la salud, particularmente entre los ...
Carolina Sanchez-Álvarez, Cristian Lermanda-Peña, Yaritza Becerra-Torres, Ignacio Astudillo-Ganora   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The Future of Education: Black Life and Our Classrooms A Moderated Panel Discussion [PDF]

, 2019
This piece is an abridged version of a panel discussion that was part of the symposium on Anti-Black State Violence Across the Americas: Power and Struggle in Brazil and the U.S., held at UC Berkeley on February 20–22, 2019, and organized by the LUTA ...
Chism-Misquitta, Muwazu, Cook, Cherrish, Gordon, C. Darius, Onã Walê Borges dos Santos, Onirê, Silva dos Santos, Andreia Beatriz   +4 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source