Results 81 to 90 of about 540,321 (312)

Gavestinel does not improve outcome after acute intracerebral hemorrhage: an analysis from the GAIN International and GAIN Americas studies [PDF]

open access: yes, 2005
<p><b>Background and Purpose:</b> Glycine Antagonist in Neuroprotection (GAIN) International and GAIN Americas trials were prospectively designed, randomized, placebo-controlled trials of gavestinel, a glycine-site antagonist and ...
Brown, D.L.   +9 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

COVID-19 vaccine equity in the Americas

open access: yesThe Lancet Regional Health. Americas, 2022
The Lancet Regional Health– Americas
doaj   +1 more source

US/Leap Quarterly Newsletter, Issue #3 [PDF]

open access: yes, 2009
The US Labor Education in the Americas Project is an independent non-profit organization that supports the basic rights of workers in Latin America, especially those who are employed directly or indirectly by U.S. companies.
US Leap
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Monitoring access barriers to health services in the Americas: a mapping of household surveys

open access: yesRevista Panamericana de Salud Pública, 2020
Natalia Houghton   +2 more
doaj   +1 more source

Characterization of 2,500 Patients with Heart Failure and Analysis of Their Optimal Medical Therapy: Insights from the AMERICCAASS Registry

open access: yesGlobal Heart
Introduction: Heart failure (HF) is a leading cause of hospitalization and mortality worldwide, emphasizing the critical role of optimal medical therapy (OMT) in improving patient outcomes.
Alex David Sotomayor-Julio   +33 more
doaj   +1 more source

The Mask Strikes Back: Blackness as Aporia in Moby-Dick and Benito Cereno

open access: yes, 2017
What is the American Gothic a reaction to? Whereas other thinkers such as Nathaniel Hawthorne locates the building blocks of the American Gothic in Puritan Christianity or Amerindian Genocide, I argue that Melville posits the genesis of chattel slavery ...
Clarke, Jerome D.
core  

Greening development finance in the Americas [PDF]

open access: yes, 2015
This repository item contains a report from the Boston University Global Economic Governance Initiative. The Global Economic Governance Initiative (GEGI) is a research program of the Center for Finance, Law & Policy, the Frederick S.
Gallagher, Kevin P., Yuan, Fei
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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