Results 141 to 150 of about 2,292 (156)

Amh/Amhr2 Signaling Causes Masculinization by Inhibiting Estrogen Synthesis during Gonadal Sex Differentiation in Japanese Flounder (Paralichthys olivaceus)

International Journal of Molecular Sciences, 2023
The anti-Müllerian hormone (Amh) is a protein belonging to the TGF-β superfamily, the function of which has been considered important for male sex differentiation in vertebrates.
Takeshi Kitano
exaly   +2 more sources

A Long Noncoding RNA, lncRNA-Amhr2, Plays a Role in Amhr2 Gene Activation in Mouse Ovarian Granulosa Cells [PDF]

Endocrinology, 2017
Anti-Mullerian hormone (AMH) is critical to the regression of Mullerian ducts during mammalian male differentiation and targets ovarian granulosa cells and testicular Sertoli and Leydig cells of adults.
Shin Matsubara, Atsushi P Kimura, Misuzu Kurihara   +2 more
exaly   +2 more sources

AMH regulates a mosaic population of AMHR2-positive cells in the ovarian surface epithelium

Journal of Biological Chemistry
The function and homeostasis of the mammalian ovary depend on complex paracrine interactions between multiple cell types. Using primary mouse tissues and isolated cells, we showed in vitro that ovarian follicles secrete factor(s) that suppresses the ...
Xiang-Xi Xu, Isaac R L Xu, Elizabeth R Smith   +2 more
exaly   +2 more sources

The Relationship between AMH and AMHR2 Polymorphisms and the Follicular Phase in Late Reproductive Stage Women

International Journal of Environmental Research and Public Health, 2016
The objective of this work was the analysis of the relationships between the genotypes of the AMH and AMH receptor type 2 genes, hormone levels and the menstrual cycle in a group of Polish women in the late reproductive stage.
Krzysztof Safranow, Małgorzata Szkup-Jabłońska, Anna Grzywacz   +2 more
exaly   +2 more sources

A dominant negative mutation at the ATP binding domain of AMHR2 is associated with a defective anti-Müllerian hormone signaling pathway.

Molecular Human Reproduction, 2016
STUDY QUESTION Does a heterozygous mutation in AMHR2, identified in whole-exome sequencings (WES) of patients with primary ovarian insufficiency (POI), cause a defect in anti-Müllerian hormone (AMH) signaling?
Kehkooi Kee, Yunxia Cao, Binbin Wang
exaly   +2 more sources

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A sex-linked SNP mutation in amhr2 is responsible for male differentiation in obscure puffer (Takifugu obscurus)

Molecular Biology Reports, 2021
Zhe Zhao, Jian-Fang Gui, Fan-Xiang Gao
exaly  

Identification of AMH and AMHR2 Variants Led to the Diagnosis of Persistent Müllerian Duct Syndrome in Three Cases

Genes, 2022
Ruzhu Lan
exaly  

Digenic Congenital Hypogonadotropic Hypogonadism Due to Heterozygous GNRH1 p.R31C and AMHR2 p.G445_L453del Variants

Genes, 2023
Bryan K Ward, Scott G Wilson, Timothy W Jones   +2 more
exaly  

A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives

Proceedings of the National Academy of Sciences of the United States of America, 2022
Patricia K. Donahoe, Marie-Charlotte Meinsohn, Lina Wei   +2 more
exaly  

Identification of four novel variant in the AMHR2 gene in six unrelated Turkish families

Journal of Endocrinological Investigation, 2020
Amine Aktar Karakaya, Ferda Özkınay, Hüseyin Onay   +2 more
exaly