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Amide–Amide Hydrogen Bonding. Semirubin Amides

Monatshefte für Chemie - Chemical Monthly, 2006
Semirubins are analogs for one-half of the bilirubin structure and capable of intramolecular hydrogen bonding. Semirubin amides of ammonia and primary amines are also capable of intramolecular hydrogen bonding. From a combination of spectroscopic methods (1H NMR, NOE, and VPO), the primary amide is found to engage very effectively in intramolecular ...
Nicholas T. Salzameda, David A. Lightner
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Peptide amidation

Trends in Biochemical Sciences, 1991
Many hormones, neurotransmitters and growth factors are peptides that carry an amide group at their carboxyl terminus which is essential for their biological activity. The amide is formed by hydroxylation of an additional glycine residue present in the biosynthetic precursor and the hydroxyglycine derivative dissociates to form the peptide amide and ...
A F, Bradbury, D G, Smyth
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Reactions of amide anions with α-bromo-amides

J. Chem. Soc., Chem. Commun., 1981
The reactions of α-bromoisobutyramides with the anions from amides and a thioamide afford oxazolidin-4-ones and a thiazolidin-4-one, respectively; these are useful intermediates for preparation of ester derivatives.
G. Cavicchioni   +3 more
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21.1.8 Synthesis of Amides by Transamidation and Amidation of Activated Amides and Esters

2020
AbstractThis chapter provides a summary of the recent advances in direct transamidation and amidation reactions of activated amides and esters via transition-metal-catalyzed and transition-metal-free C(acyl) —N and C(acyl) —O bond cleavage as a new disconnection for the synthesis of amide bonds.
G. Li, M. Szostak
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