Results 191 to 200 of about 286,543 (254)

Neophytadiene, a Plant Specialized Metabolite, Mediates the Virus‐Vector‐Plant Tripartite Interactions

open access: yesAdvanced Science, EarlyView.
Tomato chlorosis virus (ToCV) infection induces production of neophytadiene, a volatile resulting from chlorophyll degradation that is highly attractive to whiteflies. OBP2, an odorant‐binding protein from insect vector B. tabaci, exhibits a strong binding affinity for neophytadiene.
Xiao‐bin Shi   +14 more
wiley   +1 more source

Engineered Hydrogels for Organoid Models of Human Nonalcoholic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
Nonalcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation and extracellular matrix stiffening. An in vitro NAFLD model is developed using engineered hydrogels (G′ ≈ 1–6 kPa) and iPSC‐derived hepatic organoids. It is demonstrated that higher stiffness can increase lipid droplet accumulation, fibrosis, and metabolic dysregulation ...
Yueming Liu   +11 more
wiley   +1 more source

Recent Advances in mRNA Delivery Systems for Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang   +9 more
wiley   +1 more source

Predicting p<i>K</i> <sub>a</sub> of flexible polybasic tetra-aza macrocycles. [PDF]

open access: yesRSC Adv
Harvey TK   +6 more
europepmc   +1 more source

Local Charge Density Enhancement Strategy in Nitrogen‐rich Covalent Organic Framework for Boosted Iodine Removal From Water

open access: yesAdvanced Science, EarlyView.
The covalent organic framework, phen‐TPA, is designed for efficient iodine removal from aqueous solutions, featuring optimized iodine‐binding N‐sites. It shows the fastest iodine removal kinetics for I2 and the highest capacity for I3−. Large‐scale flow‐through tests demonstrate its effective separation of I2 and I3− in high‐salinity environments ...
Yue Ma   +9 more
wiley   +1 more source

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