Results 221 to 230 of about 220,378 (310)

Synthesis and properties of <i>N</i>-(trifluoromethyl)amides. [PDF]

Chem Sci
O'Duill ML, Wood IL, Brooks I, McIvor C.
europepmc   +1 more source

Kinetic‐Directed Thermodynamic Repair Enables the Synthesis of High‐Strain 2D Sub‐Stoichiometric COFs

Advanced Science, EarlyView.
2D covalent organic frameworks are promising photocatalysts. Yet, precise synthesis of sub‐stoichiometric COFs remains challenging due to poor kinetic control. We propose a general strategy: tuning polymerization degree of kinetic intermediates via time or solvent polarity directs their thermodynamic repair into highly crystallization. Using [4+3]‐type
Xiang Pei, Kaifu Yu, Pan He, Hongqing Wu, Bo Jiang, Kewen Shu, Yang Li, Ya Tang, Lijian Ma   +8 more
wiley   +1 more source

Modular in-plate synthesis of N-heterocycles for direct-to-biology screening. [PDF]

Chem Sci
Sun X, Ye Z, Guo F, Chu X, Chen Y, Li J, Yang T, Zhao B, Zhang B, Jiang S, He G, Qiao T, Lei X, Liu H, Chen G.   +14 more
europepmc   +1 more source

Freestanding Bamboo‐Like Nitrogen‐Doped Carbon Nanofibers/PANI Dual‐Conductive Cathodes via Interfacial Engineering for High‐Performance Lithium–Sulfur Batteries

Advanced Science, EarlyView.
Bamboo‐like nitrogen‐doped carbon fibers (BNCFs) were synthesized via a vapor‐liquid‐solid catalytic growth method and further integrated with polyaniline to fabricate a freestanding BNCFs/S/PANI cathode. The PANI coating and BNCFs framework synergistically establish an interconnected conductive network with abundant nitrogen‐active sites, thereby ...
Jie Yang, Fan Wang, Enci Wang, Haile Qian, Terence Xiaoteng Liu, Jiarui Huang   +5 more
wiley   +1 more source

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

Advanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun, Jinyoung Kim, Chang Gon Kim, Seokhyeong Go, Mina Han, Yujin Ouck, Soojin Jang, Seong Uk Son, Gamin Kim, Wonrak Son, Eunjung Kim, Min Hee Hong, Ja Hyun Yeo, Eun‐Kyung Lim, Hye Ryun Kim, Seungjoo Haam   +15 more
wiley   +1 more source

An Immediate‐Response Detection System for γ‐Hydroxybutyrate to Enhance Personal Safety in Social Environments

Advanced Science, EarlyView.
A graphene‐based electrical biosensor enables rapid and highly sensitive detection of GHB at 100 fm in both standard solutions and artificial urine, providing reliable point‐of‐need screening for drug‐facilitated sexual assault. The platform demonstrates strong selectivity, fast response, and a wide dynamic range, supporting accurate detection in ...
Jai Eun An, Jisung Kwak, Kyung Ho Kim, Chaeeun Kim, Sung Eun Seo, Nathaniel S. Hwang, Yong‐Sang Ryu, Hyun Seok Song, Oh Seok Kwon   +8 more
wiley   +1 more source

Storing Data With Propargylic Amines Using Thin-Layer Chromatography for the Data Retrieval. [PDF]

Chempluschem
Mateus M, Nallappan S, Rycek L.
europepmc   +1 more source

Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy

Advanced Science, EarlyView.
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li, Daishi Li, Danyao Chen, Yating Dian, Lei Yao, Hui Su, Ziyu Guo, Deze Zhao, Zihua Wu, Furong Zeng, Chunfang Zhang, Guangtong Deng   +11 more
wiley   +1 more source

Application of an improved analytical protocol for the evaluation of biogenic amines in wines produced in the Canary Islands. [PDF]

Food Chem X
Fernández-Casanova C, Heras-Roger J, Díaz-Romero C, Herrera-Herrera AV, Socas-Rodríguez B.   +4 more
europepmc   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source