Results 41 to 50 of about 197,196 (315)

Synthesis of Secondary Amines via Self-Limiting Alkylation of N-Aminopyridinium Salts [PDF]

open access: yes, 2023
Partial amine alkylation to prepare secondary amines is challenging due to the enhanced N-nucleophilicity that accompanies alkylation. Here we introduce N-aminopyridinium salts as ammonia surrogates for the synthesis of secondary amines via self-limiting
David, Powers   +4 more
core   +1 more source

4-Azidocinnoline—Cinnoline-4-amine Pair as a New Fluorogenic and Fluorochromic Environment-Sensitive Probe

open access: yesMolecules, 2021
A new type of fluorogenic and fluorochromic probe based on the reduction of weakly fluorescent 4-azido-6-(4-cyanophenyl)cinnoline to the corresponding fluorescent cinnoline-4-amine was developed.
Natalia A. Danilkina   +7 more
doaj   +1 more source

N-[(1R)-1-(4-Chlorophenyl)ethyl]-Cyanamide

open access: yesMolbank, 2021
The title compound was synthesized by electrophilic cyanation of commercially available (R)-4-chloro-α-methylbenzylamine with cyanogen bromide in diethyl ether, and isolated as a yellow oil in 84% yield.
Rebeca González-Fernández   +2 more
doaj   +1 more source

Titanium-Mediated Reduction of Carboxamides to Amines with Borane–Ammonia

open access: yesMolecules, 2023
In this study, the successful titanium tetrachloride-catalyzed reduction of aldehydes, ketones, carboxylic acids, and nitriles with borane–ammonia was extended to the reduction (deoxygenation) of a variety of aromatic and aliphatic pri-, sec- and tert ...
P. Veeraraghavan Ramachandran   +2 more
doaj   +1 more source

Amines, Astrocytes, and Arousal [PDF]

open access: yesNeuron, 2017
Amine neurotransmitters, such as noradrenaline, mediate arousal, attention, and reward in the CNS. New data suggest that, from flies to mammals, a major mechanism for amine transmitter action is to raise astrocyte [Ca2+]i and release gliotransmitters that modulate neuronal activity and behavior.
Bazargani, N, Attwell, D
openaire   +3 more sources

Facile sonochemical heterocyclization of 2,5-dimethoxy tetrahydrofuran with primary amines using sulfonated MWCNTs as a recyclable catalyst in aqueous media

open access: yesGreen Chemistry Letters and Reviews, 2017
A set of N-substituted pyrrole derivatives have been designed and synthesized using sulfonated multi-walled carbon nanotubes as a recyclable heterogeneous catalyst under ultrasound irradiation.
Hossein Naeimi, Mahla Dadaei
doaj   +1 more source

Understanding the multifaceted nature of peptide hydrogels in biomedical research

open access: yesAcademia Materials Science
Hydrogels are networks of three-dimensional cross-linked polymers, which possess the capacity to absorb and retain water. Hydrogels have proven to be adaptable and versatile, making them useful in various biomedical applications such as tissue
Srestha Ghosh   +3 more
doaj   +1 more source

Septic encephalopathy: does inflammation drive the brain crazy?

open access: yesBrazilian Journal of Psychiatry, 2014
Sepsis and the multiorgan dysfunction syndrome are among the most common reasons for admission to an intensive care unit, and are a leading cause of death.
Felipe Dal-Pizzol   +2 more
doaj   +1 more source

Sympathomimetic Amines [PDF]

open access: yesAnaesthesia and Intensive Care, 1980
The autonomic nervous system may play an important role in tissue autoregulation as the neurohumoral transmission process has been shown to constitute the final common pathway by which the effects of many physiological and pharmacological substances are mediated.
openaire   +2 more sources

Synthesis of Novel IP Agonists via N-Aminoethyl Cyclic Amines Prepared by Decarboxylative Ring-Opening Reactions

open access: yesMolecules, 2012
An efficient synthesis of a highly potent and selective IP (PGI2 receptor) agonist that is not structurally analogous to PGI2 is described. This synthesis is accomplished through the following key steps: Nucleophilic ring-opening of 3-(4-chlorophenyl ...
Masashi Uchida   +8 more
doaj   +1 more source

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