Results 41 to 50 of about 226,914 (312)
Green Chemistry Letters and Reviews, 2017 A set of N-substituted pyrrole derivatives have been designed and synthesized using sulfonated multi-walled carbon nanotubes as a recyclable heterogeneous catalyst under ultrasound irradiation.
Hossein Naeimi, Mahla Dadaei
doaj +1 more source
Septic encephalopathy: does inflammation drive the brain crazy?
Brazilian Journal of Psychiatry, 2014 Sepsis and the multiorgan dysfunction syndrome are among the most common reasons for admission to an intensive care unit, and are a leading cause of death.
Felipe Dal-Pizzol +2 more
doaj +1 more source
Molecules, 2012 An efficient synthesis of a highly potent and selective IP (PGI2 receptor) agonist that is not structurally analogous to PGI2 is described. This synthesis is accomplished through the following key steps: Nucleophilic ring-opening of 3-(4-chlorophenyl ...
Masashi Uchida +8 more
doaj +1 more source
Photoinduced Deaminative Borylation of Unactivated Aromatic Amines Enhanced by CO2 [PDF]
, 2021 Herein, direct unactivated C-N borylation of aromatic amines by a photocatalyst was achieved under mild and metal-free conditions. The C-N borylation of aromatic amines with bis(pinacolato)diboron (B2pin2) proceeded in the presence of a pyrene catalyst ...
Yoichiro, Kuninobu +2 more
core +2 more sources
, 2019 Bicyclo[1.1.1]pentanes are effective bioisoteres for aromatic rings, tert-butyl groups, and alkynes. Here we report the first method to synthesize 3-alkylbicyclo[1.1.1]pentan-1-amines directly from [1.1.1]propellane via sequential addition of ...
Jonathan M. E. Hughes (6912470) +4 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2023 A Pd-catalyzed cyclization reaction of 2-(2-vinylarene)acetonitriles and isocyanides has been documented. Various naphthalen-2-amines were obtained in moderate to good yields under mild conditions.
Huishu Lin (16826691) +15 more
core +1 more source
Cu-Catalysed Coupling of Aliphatic Amines with Alkylboronic Esters [PDF]
, 2023 We report a Cu-catalysed oxidative coupling of aliphatic amines with benzylic and aliphatic boronic esters to give high value alkyl amines, products found widely in applications from medicinal chemistry to materials science.
Antonio, Romero Arenas +6 more
core +2 more sources
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Synthesis Of Secondary Amines Via N-(Benzoyloxy)Amines And Organoboranes
, 1999 A variety of primary amines (R-NH2) were converted to their corresponding N-(benzoyloxy)amines (i.e., R-NHOCOPh) under biphasic conditions in excellent yields (63-90%).
Phanstiel IV, O. +7 more
core +2 more sources