Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm. [PDF]
SNPs (single nucleotide polymorphisms) on a chromosome 16 locus encompassing FTO, as well as IRX3, 5, 6, FTM and FTL are robustly associated with human obesity.
Antrobus, Robin +6 more
core +2 more sources
The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases [PDF]
Janthinobacteria commonly form biofilms on eukaryotic hosts and are known to synthesize antibacterial and antifungal compounds. Janthinobacterium sp. HH01 was recently isolated from an aquatic environment and its genome sequence was established.
Blokesch, Melanie +20 more
core +4 more sources
Structure of the ArgRS-GlnRS-AIMP1 complex and its implications for mammalian translation [PDF]
In higher eukaryotes, one of the two arginyl-tRNA synthetases (ArgRSs) has evolved to have an extended N-terminal domain that plays a crucial role in protein synthesis and cell growth and in integration into the multisynthetase complex (MSC).
CHO, YUNJE +14 more
core +1 more source
The compositional and evolutionary logic of metabolism
Metabolism displays striking and robust regularities in the forms of modularity and hierarchy, whose composition may be compactly described. This renders metabolic architecture comprehensible as a system, and suggests the order in which layers of that ...
Alberts B +75 more
core +1 more source
EST analysis of gene expression in early cleavage-stage sea urchin embryos [PDF]
A set of 956 expressed sequence tags derived from 7-hour (mid-cleavage) sea urchin embryos was analyzed to assess biosynthetic functions and to illuminate the structure of the message population at this stage.
Britten, Roy J. +6 more
core
Cyclosporin A-binding protein (cyclophilin) of Neurospora crassa [PDF]
Cyclophilin (cyclosporin A-binding protein) has a dual localization in the mitochondria and in the cytosol of Neurospora crassa. The two forms are encoded by a single gene which is transcribed into mRNAs having different lengths and 5' termini ...
Hartl, Franz-Ulrich +6 more
core
Publications of the exobiology program for 1981: A special bibliography [PDF]
The exobiology program investigates the planetary events which were responsible for, or, related to, the origin, evolution, and distribution of life in the universe.
Devincenzi, D. L., Pleasant, L. G.
core +1 more source
Co-Translational Incorporation of <i>(R)</i>- and <i>(S)</i>-β<sup>2</sup>-Hydroxy Acids <i>In Vitro</i>: A Structural and Biochemical Study on the <i>E. coli</i> Ribosome. [PDF]
Majumdar C +6 more
europepmc +1 more source
Expanding the Genetic Code with Lysine Aminoacylation. [PDF]
Li X, Gan Q, Fan C.
europepmc +1 more source

