Recent Advances in Chemical Synthesis of Amino Sugars [PDF]
Molecules, 2023 Amino sugars are a kind of carbohydrates with one or more hydroxyl groups replaced by an amino group. They play crucial roles in a broad range of biological activities.
Jian Yang, Demeng Xie, Xiaofeng Ma
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Significant release and microbial utilization of amino sugars and D-amino acid enantiomers from microbial cell wall decomposition in soils. [PDF]
Soil Biol Biochem, 2018 Amino sugars and D-amino acid enantiomers are major components of bacterial and fungal cell walls (i.e. peptidoglycan and chitin) and are often used as biomarkers of microbial residue turnover in soils.
Hu Y, Zheng Q, Zhang S, Noll L, Wanek W.
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Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars [PDF]
Open Biology, 2016 Mycobacterium tuberculosis (Mtb), the aetiological agent of tuberculosis, has evolved to scavenge nutrients from the confined environment of host macrophages with mycobacterial ATP-binding cassette (ABC) transporters playing a key role in nutrient ...
Elizabeth Fullam +3 more
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Amino Sugars Reshape Interactions between Streptococcus mutans and Streptococcus gordonii. [PDF]
Appl Environ Microbiol, 2020 Carbohydrate metabolism is central to the development of dental caries. A variety of sugars available to dental microorganisms influence the development of caries by affecting the physiology, ecology, and pathogenic potential of tooth biofilms. Using two
Chen L, Walker AR, Burne RA, Zeng L.
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Amino Sugars Modify Antagonistic Interactions between Commensal Oral Streptococci and Streptococcus mutans. [PDF]
Appl Environ Microbiol, 2019 Dental caries is driven by dysbiosis of oral biofilms in which dominance by acid-producing and acid-tolerant bacteria results in loss of tooth mineral. Our previous work demonstrated the beneficial effects of amino sugars GlcNAc and GlcN in promoting the
Chen L +4 more
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The Effect of Amino Sugars on the Composition and Metabolism of a Microcosm Biofilm and the Cariogenic Potential against Teeth and Dental Materials [PDF]
Journal of Functional Biomaterials, 2022 Amino sugars N-acetylglucosamine (GlcNAc) and glucosamine (GlcN) are abundant sources of carbon and nitrogen in the oral cavity. The aim of this study was to investigate the effects of GlcNAc metabolism on the genomics and biochemistry of a saliva ...
Lin Zeng +5 more
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Synthesis of O-Amino Sugars and Nucleosides [PDF]
Molecules, 2018 Nucleic acids and carbohydrates are essential biomolecules involved in numerous biological and pathological processes. Development of multifunctional building blocks based on nucleosides and sugars is in high demand for the generation of novel ...
Na Chen, Juan Xie
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Chemical Synthesis of Rare, Deoxy-Amino Sugars Containing Bacterial Glycoconjugates as Potential Vaccine Candidates. [PDF]
Molecules, 2018 Bacteria often contain rare deoxy amino sugars which are absent in the host cells. This structural difference can be harnessed for the development of vaccines. Over the last fifteen years, remarkable progress has been made toward the development of novel
Behera A, Kulkarni SS.
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Optimizing sample pretreatment for compound-specific stable carbon isotopic analysis of amino sugars in marine sediment [PDF]
Biogeosciences, 2014 Amino sugars are quantitatively significant constituents of soil and marine sediment, but their sources and turnover in environmental samples remain poorly understood.
R. Zhu +4 more
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Flux Analysis of Free Amino Sugars and Amino Acids in Soils by Isotope Tracing with a Novel Liquid Chromatography/High Resolution Mass Spectrometry Platform. [PDF]
Anal Chem, 2017 Soil fluxomics analysis can provide pivotal information for understanding soil biochemical pathways and their regulation, but direct measurement methods are rare.
Hu Y, Zheng Q, Wanek W.
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