Results 71 to 80 of about 3,027 (250)

Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast

open access: yes, 2015
The organic anion transporter OAT4 (SLC22A11) and organic anion transporting polypeptide OATP2B1 (SLCO2B1) are expressed in the basal membrane of the placental syncytiotrophoblast.
Brooks, S.   +6 more
core   +1 more source

Surface modification with P-aminohippuric acid on biogenic apatite (fish bones) particles

open access: yesMarine Science and Technology Bulletin, 2014
The aim of this study with fish bones as a waste in fish processing is to investigate whether they can provide more efficient and multi-functional materials by chemical modification.
Evren Tan   +4 more
doaj  

Effects of levosimendan on renal blood flow and glomerular filtration in patients with acute kidney injury after cardiac surgery: a double blind, randomized placebo-controlled study

open access: yesCritical Care, 2021
Background Acute kidney injury (AKI) is a common and serious complication after cardiac surgery, and current strategies aimed at treating AKI have proven ineffective.
Maria Tholén   +2 more
doaj   +1 more source

Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11) [PDF]

open access: yes, 2013
Active components of complementary/alternative medicines and natural supplements are often anionic compounds and flavonoids. As such, organic anion transporters (OATs) may play a key role in their pharmacokinetic and pharmacological profiles, and ...
Sweet, Douglas H., Wang, Li
core   +3 more sources

Effects of patent foramen ovale in migraine: a metabolomics‐based study

open access: yesThe Journal of Physiology, Volume 603, Issue 4, Page 809-835, 15 February 2025.
Abstract figure legend Aura, cystatin‐C and calcium are biomarkers of PFO in migraine. PFO closure relieves migraine by regulating 5‐HT metabolism and redox reactions, especially in the posterior head. cTTE, contrast‐transthoracic echocardiography; DESI‐MSI, desorption electrospray ionization mass imaging; H&E, haematoxylin and eosin; PFO, patent ...
Bosi Dong   +15 more
wiley   +1 more source

Human Organic Anion Transporter 4 Is a Renal Apical Organic Anion/Dicarboxylate Exchanger in the Proximal Tubules

open access: yesJournal of Pharmacological Sciences, 2004
Human organic anion transporter OAT4 is expressed in the kidney and placenta and mediates high-affinity transport of estrone-3-sulfate (E1S). Because a previous study demonstrated no trans-stimulatory effects by E1S, the mode of organic anion transport ...
Sophapun Ekaratanawong   +8 more
doaj   +1 more source

Rapid hepatic clearance of full length CCN-2/CTGF: a putative role for LRP1-mediated endocytosis [PDF]

open access: yes, 2016
CCN-2 (connective tissue growth factor; CTGF) is a key factor in fibrosis. Plasma CCN-2 has biomarker potential in numerous fibrotic disorders, but it is unknown which pathophysiological factors determine plasma CCN-2 levels.
Bovenschen, N. (N.)   +8 more
core   +6 more sources

Use of Living Donors in Kidney Transplantation in Man [PDF]

open access: yes, 1970
A series is presented of 238 living renal donors who have been followed for periods of from eight months to eight years. Careful selection of donors is mandatory in order to avoid postoperative mortality or morbidity. Anatomic variations which may affect
Halgrimson, CG   +3 more
core   +1 more source

Screening study of hydroxytyrosol metabolites from in vitro fecal fermentation and their interaction with intestinal barrier repair receptor AhR

open access: yesJournal of Food Science, Volume 89, Issue 12, Page 10134-10151, December 2024.
Abstract Olive oil polyphenol hydroxytyrosol (HT) significantly repairs intestinal barrier function, but its absorption in the stomach and small intestine is limited. The metabolites of unabsorbed HT that reach the colon are crucial, yet their effects on colonic microbiota and intestinal barrier repair remain unclear.
Yuqing Song   +7 more
wiley   +1 more source

Blood L‐cystine levels positively related to increased risk of hypertension

open access: yesThe Journal of Clinical Hypertension, Volume 26, Issue 12, Page 1411-1423, December 2024.
Abstract Hypertension is one component of metabolic syndrome (MetS). Here, the study evaluated hypertension‐associated metabolites in relation to other MetS components. Fasting plasma samples were collected from 22 hypertensive and 63 normotensive subjects for non‐targeted metabolomics.
Haijun Chen   +7 more
wiley   +1 more source

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