Structural insights into human polyspecific organic anion transporters OAT1 and OAT4
Cell ReportsSummary: Organic anion transporters (OATs) play a critical role in the transport of organic anions. OAT1, located in the kidney, is essential for the transport of organic anion drugs and metabolites, while OAT4 facilitates absorption processes in the ...
Wei Zhang +7 more
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The Development of a Direct Homologous Radioimmunoassay for Serum Cortisol [PDF]
, 1981 Peer ...
Giesemann, G. +4 more
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Frontiers in Pharmacology, 2019 Pediatric drug development, especially in disease areas that only affect children, can be stimulated by using juvenile animal models not only for general safety studies, but also to gain knowledge on the pharmacokinetic and pharmacodynamic properties of ...
Joske Millecam +10 more
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Net hepatic release of glucose from precursor supply in ruminants: a meta-analysis
Animal, 2020 For their glucose supply, ruminants are highly dependent on the endogenous synthesis in the liver, but despite the numerous studies that evaluated hepatic glucose production, very few simultaneously measured hepatic glucose production and uptake of all ...
C. Loncke +7 more
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Evaluation of the transporter-mediated herb-drug interaction potential of DA-9801, a standardized dioscorea extract for diabetic neuropathy, in human in vitro and rat in vivo [PDF]
, 2014 BACKGROUND: Drug transporters play important roles in the absorption, distribution, and elimination of drugs and thereby, modulate drug efficacy and toxicity. With a growing use of poly pharmacy, concurrent administration of herbal extracts that modulate
Eun Nam Kim +8 more
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Probabilistic Modelling of Liquid Chromatography Time-of-Flight Mass Spectrometry
, 2011 Liquid Chromatography Time-of-Flight Mass Spectrometry (LC-TOFMS) is an analytical platform that is widely used in the study of biological mixtures in the rapidly growing fields of proteomics and metabolomics.
Ipsen, Andreas, Ipsen, Andreas
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AtPHT4;4 is a chloroplast-localized ascorbate transporter in Arabidopsis [PDF]
, 2015 Ascorbate is an antioxidant and coenzyme for various metabolic reactions in vivo. In plant chloroplasts, high ascorbate levels are required to overcome photoinhibition caused by strong light.
Kuromori, Takashi +10 more
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Inulin and para-aminohippuric acid: determinants of glomerular filtration rate and renal blood flow following single intravenous bolus injection in man [PDF]
, 1990 J. A. N. McAuslane
openalex +3 more sources
Mammary blood flow and metabolic activity are linked by a feedback mechanism involving nitric oxide synthesis [PDF]
, 2014 To test which, if any, of the major milk precursors can elicit a rapid change in the rate of mammary blood flow (MBF) and to define the time course and magnitude of such changes, 4 lactating cows were infused with glucose, amino acids, or triacylglycerol
Cant J.P. +5 more
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Surgical cyst decortication in autosomal dominant polycystic kidney disease [PDF]
, 2013 PURPOSE: To provide a summary of the relevant literature regarding the impact of surgical cyst decortication on hypertension, renal function, and pain management in patients with autosomal dominant polycystic kidney disease (ADPKD).
Bhayani, Sam B +5 more
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