Abstract Brain tumour segmentation employing MRI images is important for disease diagnosis, monitoring, and treatment planning. Till now, many encoder‐decoder architectures have been developed for this purpose, with U‐Net being the most extensively utilised. However, these architectures require a lot of parameters to train and have a semantic gap. Some
Muhammad Zeeshan Aslam +3 more
wiley +1 more source
Isocitrate dehydrogenase 1 mutations drive downregulation of IL1R1 and dysregulated inflammatory response in acute myeloid leukemia. [PDF]
Steinhäuser S +21 more
europepmc +1 more source
Habitat Features, Coyotes, and Humans Drive Diel Activity Variation Among Sympatric Mammals
We found that multiple mammal species show considerable variation in diel activity in response to several factors, with biotic variables (habitat features and the presence of coyotes Canis latrans) having the strongest overall effects. Our results have important implications for trophic dynamics. Future studies will need to account for these underlying
Nathan J. Proudman, Maximilian L. Allen
wiley +1 more source
Characterizing <i>KMT2A</i> Rearrangement in Acute Myeloid Leukemia: A Comprehensive Genomic Study. [PDF]
Batayneh O +12 more
europepmc +1 more source
Combined FLT3 and EZH1/2 inhibition reduces LSCs and promotes myeloid differentiation in PDX models of AML [PDF]
Murugan Selvam +6 more
openalex +1 more source
BRD9 inhibition as potential treatment option for testicular germ cell tumors
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen +5 more
wiley +1 more source
Is There a Future for CAR-T Therapy in Acute Myeloid Leukemia? [PDF]
Alati C +11 more
europepmc +1 more source
Real-world patterns of treatment intensity and prognostic model performance in older AML: Insights from the french ALFA-PPP cohort [PDF]
Lin-Pierre Zhao +35 more
openalex +1 more source
“Flames Over Persepolis”: New Scientific Evidence Supporting Historical Perspectives
ABSTRACT This study investigates the burning of Persepolis Terrace, historically attributed to Alexander III in 330 bce. A review of classical accounts and excavation reports, combined with diagnostic surveys, confirms the fire's historicity and provides novel insights.
Maria Letizia Amadori +10 more
wiley +1 more source

