Results 201 to 210 of about 219,440 (288)

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source

Relationships between age at diagnosis, clinical features, and outcome of therapy in children treated in the Medical Research Council AML 10 and 12 trials for acute myeloid leukemia [PDF]

, 2001
David Webb, G Harrison, R. F. Stevens, Brenda Gibson, Ian Hann, Keith Wheatley   +5 more
openalex   +1 more source

Reply: “Letter to the Editors: Comments on ‘Clinical and Imaging Correlates of Medication Reduction in Globus Pallidus Stimulation for Parkinson's Disease’”

Movement Disorders Clinical Practice, EarlyView.
Daniel G. Di Luca, Suneil K. Kalia, Andres M. Lozano, Alfonso Fasano   +3 more
wiley   +1 more source

Push Forward Clinical Management of Hematological Toxicity due to Lenalidomide Overexposure: Model‐Informed Precision Dosing for Chinese Population With Renal Insufficiency

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Dose‐dependent hematological toxicity of lenalidomide has been reported previously, and thus, there is a clinical need for dose individualization to manage toxicities. The objectives of this study were to explore optimal individualized dosing regimens for Chinese B‐cell malignancies patients with varying degrees of renal function, and to push ...
Yi Ma, Zaiwei Song, Hao Bing, Huan He, Libo Zhao, Rongsheng Zhao   +5 more
wiley   +1 more source

New Strategies in the Treatment of Acute Myelogenous Leukemia (AML): In Vitro Culture of AML Cells—The Present Use in Experimental Studies and the Possible Importance for Future Therapeutic Approaches [PDF]

, 2001
Øystein Bruserud, Bjørn Tore Gjertsen, Brynjar Foss, Tien‐sheng Huang   +3 more
openalex   +1 more source

Cerebellar Dentate Cavernoma Enlargement and Tremor Emergence: Longitudinal Neuroimaging Analysis of Case Report and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Andrew Z. Yang, Tiffany Rodrigues, Sriranga Kashyap, Yash Patel, Arjun Balachandar, Benjamin A. Davidson, Can Sarica, Rafael E. Buongermini, Artur Vetkas, Abu Bakar Butt, Jurgen Germann, Alfonso Fasano, Suneil K. Kalia, Andres M. Lozano, Marie Slegr, Alexandre Boutet   +15 more
wiley   +1 more source

Comparison of ‘sequential’ versus ‘standard’ chemotherapy as re‐induction treatment, with or without cyclosporine, in refractory/relapsed acute myeloid leukaemia (AML): results of the UK Medical Research Council AML‐R trial [PDF]

, 2001
John A. Liu Yin, Keith Wheatley, J. K. H. Rees, Alan K. Burnett   +3 more
openalex   +1 more source

Circumvention of ara-C resistance by aphidicolin in blast cells from patients with AML [PDF]

, 2001
Jean Sargent, A. W. Elgie, Christine Williamson, Grażyna Lewandowicz, Colin G. Taylor   +4 more
openalex   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Analyzing functional genomic differences yields oncogenes and chromosomal breakpoints in ALL and AML [PDF]

, 2001
Atul J. Butte, Ben Y. Reis, Alvin T. Kho, Yao Sun, Isaac S. Kohane   +4 more
openalex   +1 more source