Results 221 to 230 of about 161,793 (289)

Targeting MCL‐1 and MAPK overcomes venetoclax resistance in FLT3‐ITD‐positive AML cells harbouring activating PTPN11 (SHP‐2) mutations

open access: yesBritish Journal of Haematology, EarlyView.
Summary Venetoclax (VEN)‐based therapies have improved the treatment of acute myeloid leukaemia (AML); however, the emergence of resistance remains a major limitation. Mutations in protein tyrosine phosphatase (PTP) non‐receptor type 11 (PTPN11) and FMS like tyrosine kinase 3 with internal tandem duplication (FLT3‐ITD) are common in resistant patients ...
Maximilian Fleischmann   +12 more
wiley   +1 more source

[Clinical characteristics and prognostic analysis of pediatric acute myeloid leukemia with -7/7q- abnormalities]. [PDF]

open access: yesZhongguo Dang Dai Er Ke Za Zhi
Zheng FY   +6 more
europepmc   +1 more source

Haploidentical bone marrow transplantation for AML in remission after TBF conditioning: a long-term follow-up

open access: gold
Anna Maria Raiola   +16 more
openalex   +1 more source

Clinical outcomes and safety in patients with lower‐risk myelodysplastic syndromes treated with imetelstat: Substudy of the phase 3 IMerge trial

open access: yes
British Journal of Haematology, EarlyView.
Rami S. Komrokji   +20 more
wiley   +1 more source

Dominant TET2 mutations predict adverse prognosis in cytogenetically normal acute myeloid leukemia patients. [PDF]

open access: yesFront Oncol
Hao Z   +14 more
europepmc   +1 more source

Real‐world experience with CPX‐351 for secondary acute myeloid leukaemia: Comparison with FLAG‐IDA in a propensity score matching analysis

open access: yes
British Journal of Haematology, EarlyView.
Maria Agustina Perusini   +19 more
wiley   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

open access: yesCancer Science, EarlyView.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki   +3 more
wiley   +1 more source

Spectral-acoustic-coordinated astigmatic metalens for wide field-of-view and high spatiotemporal resolution 3D imaging. [PDF]

open access: yesLight Sci Appl
Gong S   +11 more
europepmc   +1 more source

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