Results 231 to 240 of about 219,440 (288)

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Unraveling the intersection of sleep disorders and erectile dysfunction: Outcomes from two EPISONO editions

Andrology, EarlyView.
Abstract Background There is growing interest in the relationship between sleep disorders and erectile dysfunction. We present the results from a 2015 follow‐up study in relation to the 2007 edition of Epidemiologic Sleep Study (EPISONO), a population‐based sleep study conducted in São Paulo, Brazil, and from the 4th edition of EPISONO (2018), with ...
Monica Levy Andersen, Allan Saj Porcacchia, Guilherme Luiz Fernandes, Tathiana A. Alvarenga, Sergio Tufik   +4 more
wiley   +1 more source

Singapore upon the Korea Strait? Cyberlibertarian Desires and Anxious Regulation in Busan's Blockchain Regulation Free Zone

Antipode, EarlyView.
Abstract This article examines the intersection of Asia's blockchain industry and special economic zones (SEZs). SEZs have been promoted to localise blockchain technology by disparate actors from cyberlibertarian figures to Asian blockchain firms, national policymakers, and local politicians.
Jamie Doucette, Seung‐Ook Lee
wiley   +1 more source

Oral Doxycycline Was a Safe and Feasible Treatment in Young Children With Neuroborreliosis

Acta Paediatrica, EarlyView.
ABSTRACT Aim There is limited evidence on the use of oral doxycycline in young children. We evaluated the feasibility and effectiveness of doxycycline in children under 9 years with neuroborreliosis. Methods This retrospective study included all children under 9 years of age treated for neuroborreliosis in the Capital Region of Denmark from 2019 to ...
Joakim Bloch, Lisbeth Schmidt, Nadja Vissing, Jonathan Peter Glenthøj, Birgitte Smith, Alfred Peter Born, Anja Poulsen, Anne‐Mette Lebech, Ulrikka Nygaard   +8 more
wiley   +1 more source

Gender blindness in the ‘Next Generation European Union’ funds: Projects for Economic Recovery and Transformation social economy as an exception to the rule

Annals of Public and Cooperative Economics, EarlyView.
Abstract This study provides empirical evidence that European Union (EU)‐funded economic recovery policies, in particular Next Generation EU (NGEU), reinforce rather than mitigate gender inequalities. By analysing Spain's Strategic Projects for Economic Recovery and Transformation (PERTEs) through Input–Output Models, the research shows that ...
María Bastida, Miguel Á. Vázquez Taín, Alberto Vaquero García, María Luisa del Río Araújo   +3 more
wiley   +1 more source

Long‐term outcome after allogeneic stem cell transplantation for GATA2 deficiency: An analysis of 67 adults and children from France and Belgium

British Journal of Haematology, EarlyView.
The overall survival of patients receiving an allogeneic haematopoietic stem cell transplant (HSCT) for GATA2 deficiency was significantly better if they were transplanted recently, with a bone marrow or cord blood graft and if the transplant was performed before the onset of excess blast. Excess blast before HSCT was the only factor associated with an
Flore Sicre de Fontbrune, Florian Chevillon, Mony Fahd, Kristell Desseaux, Xavier Poiré, Edouard Forcade, Arthur Sterin, Bénédicte Neven, Virginie Gandemer, Sylvain Thepot, Alice Garnier, Bruno Lioure, Ambroise Marcais, Stephanie Nguyen‐Quoc, Suzanne Tavitian, Laure Vincent, Jean Donadieu, Matthieu Resche Riggon, Sylvie Chevret, Marlene Pasquet, Regis Peffault de Latour   +20 more
wiley   +1 more source

Outcomes among non‐Western immigrant patients and Danish‐born patients with acute myeloid Leukaemia: A Danish population‐based cohort study

British Journal of Haematology, EarlyView.
Summary Non‐Western immigrant patients (NWIPs) may be a vulnerable population when diagnosed and treated for acute myeloid leukaemia (AML). Here we report selected quality parameters related to diagnosis, treatment, and outcome of newly diagnosed AML among NWIPs (n = 119) and Danish‐born patients (DBPs) (n = 4689). No adjusted differences were observed
Daniel Tuyet Kristensen, Mikkel Runason Simonsen, Anne Stidsholt Roug, Claus Werenberg Marcher, Andreas Due Ørskov, Anne Louise Tøllbøll Sørensen, Tarec Christoffer El‐Galaly, Joachim Baech   +7 more
wiley   +1 more source

Genocopy of EVI1‐AML with paraneoplastic diabetes insipidus: PRDM16 overexpression by t(1;2)(p36;p21) and enhancer hijacking

British Journal of Haematology, EarlyView.
Summary Diabetes insipidus (DI) in patients with acute myeloid leukaemia (AML) and chromosome 3q alterations (EVI1/PRDM3/MECOM overexpression) constitutes a poorly understood paraneoplasia. A 44‐year‐old patient presented with clinical and morphological features of this syndrome but, surprisingly, disclosed the rare translocation t(1;2)(p36;p21), with ...
Julian List, Etienne Sollier, Fiona Brown‐Burke, Katherine Kelly, Dietmar Pfeifer, Valeria Shlyakhto, Kristina Maas‐Bauer, Milena Pantic, Christoph Plass, Michael Lübbert   +9 more
wiley   +1 more source

Real‐life experience of luspatercept in transfusion‐dependent lower risk myelodysplastic syndrome patients

British Journal of Haematology, EarlyView.
This retrospective multicentre study included 98 TD LR‐MDS patients who had failed prior erythropoietin treatment and were subsequently treated with luspatercept. Red blood cell (RBC) transfusion requirements were recorded in the last 16 weeks before luspatercept initiation and response rates consecutively declined in patient groups receiving 1–2 ...
Anthi Bouchla, Sotirios G. Papageorgiou, Ioannis Kotsianidis, Panagiotis Diamantopoulos, Eleni Gavriilaki, Eleni Bouronikou, Argiris Symeonidis, Panagiotis Zikos, Mustafa Cetiner, Efthymia Vlachaki, Akrivi Kostourou, Athanasios Galanopoulos, Eleftheria Hatzimichael, Elisavet‐Christina Vervesou, Sinem Civriz Bozdağ, Nora‐Athina Viniou, Dimitrios Christoulas, Maria Dellatola, Maria Papaioannou, Menelaos Papoutselis, Dimitra Vlachopoulou, Antonia Syrigou, Maria Mainou, Sofia Chatzileontiadou, Vasiliki Pappa   +24 more
wiley   +1 more source

Genomic variant profiling in blast‐phase paediatric chronic myeloid leukaemia: Predisposing and driving alterations

British Journal of Haematology, EarlyView.
To identify pathogenic somatic and germline gene variants associated with blast‐phase transformation and cancer predisposition in paediatric chronic myeloid leukaemia (CML), n = 19 patients with blast‐phase paediatric CML were analysed with whole genome and targeted panel sequencing and compared to n = 19 patients with chronic phase paediatric CML.
Yvonne Lisa Behrens, Thea Reinkens, Winfried Hofmann, Amelie Gumann, Alisa Förster, Laura Gaschler, Tabita Ghete, Renate Strasser, Jennifer Espenkötter, Bernd Haermeyer, Michaela Losch, Stephanie Sembill, Zofia Wotschofsky, Stephan von Hörsten, Wolfgang Schuh, Nataliya Di Donato, Meinolf Suttorp, Manuela Krumbholz, Tim Ripperger, Brigitte Schlegelberger, Gudrun Göhring, Markus Metzler, Axel Karow   +22 more
wiley   +1 more source