Results 71 to 80 of about 26,012 (179)

EFFICACY AND SAFETY OF AMLODIPINE MALEATE IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND BRONCHIAL ASTHMA WITH CONCOMITANT ARTERIAL HYPERTENSION

Рациональная фармакотерапия в кардиологии, 2016
Aim. To evaluate efficacy and safety of amlodipine maleate in patients with chronic obstructive pulmonary disease (COPD), bronchial asthma (BA) and concomitant arterial hypertension.Methods.
N. A. Karoli, A. P. Rebrov, A. A. Roshchina, V. A. Sergeeva, E. E. Arkhangelskaya   +4 more
doaj   +1 more source

Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei, Atefeh Taghavi, Amir R. Afshari, Farzaneh Davoudi, Elaheh Gheybi, Mohammad Jalili‐Nik   +5 more
wiley   +1 more source

Effect of Amlodipine on The Concentration of Carotid Tissue Endothelin in High Cholesterol Fed Rabbits

پزشکی بالینی ابن سینا, 2008
Introduction & Objective: Endothelin-1 is involved in induction and progression of atherosclerosis. Since several changes with abnormality in transferring of calcium ions have been seen in atherosclerotic vessels, it is supposed that calcium channel ...
Mostafa Mohammadi, Fariba Mirzaie, Iraj Salehi   +2 more
doaj  

Impact of CYP2C19 and CYP3A4 Inhibitor Use on Clopidogrel Clinical Effectiveness in CYP2C19 Genotyped Patients Undergoing Percutaneous Coronary Intervention

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 531-541, August 2026.
CYP2C19 and CYP3A4 contribute to clopidogrel bioactivation. CYP2C19 no‐function alleles diminish clopidogrel's antiplatelet effects and clinical effectiveness. Coadministration of either a CYP2C19 or a CYP3A4 inhibitor may also reduce clopidogrel's antiplatelet effects and lead to phenoconversion in patients without a CYP2C19 no‐function allele (normal/
Danwei Shao, Jean G. Malavé, Joseph S. Rossi, Francesco Franchi, Ellen C. Keeley, Dominick J. Angiolillo, George A. Stouffer, Larisa H. Cavallari, Craig R. Lee   +8 more
wiley   +1 more source

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

ELECTROPHORESIS, Volume 47, Issue 8, Page 696-712, August 2026.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source

Gingival enlargement and dentition loss associated with disseminated Cryptococcus neoformans infection in a dog

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 1‐year‐old, female, spayed, mixed‐breed dog was examined by a referring veterinarian for a 1‐week history of sneezing, bilateral mucoid nasal discharge, mild bilateral ocular discharge and stertor. During rhinoscopy, a plant awn foreign body was removed, but upper respiratory signs persisted. Computed tomography of the head revealed findings
Glynn Woods, Allison Volk, Janny Evenhuis, Abbie Metcalfe, Jane E. Sykes   +4 more
wiley   +1 more source

Comparisons of the pharmacokinetics and tolerability of fixed-dose combinations of amlodipine besylate/losartan and amlodipine camsylate/losartan in healthy subjects: a randomized, open-label, single-dose, two-period, two-sequence crossover study

Drug Design, Development and Therapy, 2016
YoonJung Choi,1 SeungHwan Lee,2 Sang-Min Cho,3 Won-Ho Kang,3 Kyu-Yeol Nam,4 In-Jin Jang,1 Kyung-Sang Yu1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine, 2Clinical Trials Center, Seoul National ...
Choi Y, Lee S, Cho SM, Kang WH, Nam KY, Jang IJ, Yu KS   +6 more
doaj  

Exceptional Response of HER2‐Positive Breast Cancer to Osimertinib: A Case Report

Thoracic Cancer, Volume 17, Issue 16, August 2026.
An 83‐year‐old woman with synchronous EGFR L858R‐mutated lung adenocarcinoma and HER2‐positive breast cancer received osimertinib monotherapy for lung cancer without breast‐directed therapy. The breast tumor showed durable radiological and metabolic regression, with a Grade 3 therapeutic effect and HER2 amplification confirmed at postmortem biopsy ...
Hirotoshi Yasui, Misaki Hatasa, Ko Ohara, Kaito Sano, Yasutaka Mori, Tomofumi Shibata, Yasutaka Fukui, Mitsuru Odate, Yoshifumi Arai, Masahiro Fujii, Yasushi Makino   +10 more
wiley   +1 more source

Performance of Primary Aldosteronism Screening Tests Before Washout of Dihydropyridine Calcium Channel Blockers: An Exploratory Retrospective Study

The Journal of Clinical Hypertension, Volume 28, Issue 8, August 2026.
ABSTRACT This retrospective cohort study preliminarily investigated the feasibility of implementing primary aldosteronism (PA) screening without discontinuing dihydropyridine calcium channel blockers (DHP‐CCBs). We screened all patients undergoing diagnostic testing for secondary hypertension from January 2017 to May 2022 at authors’ center.
Xinyu Liu, Zhe Gu, Sufang Hao, Hui Dong, Wei Zhang, Huimin Zhang, Haiying Wu, Ying Lou, Jin Bian, Wenjun Ma   +9 more
wiley   +1 more source

Adherence with single-pill amlodipine/atorvastatin vs a two-pill regimen

Vascular Health and Risk Management, 2008
Bimal V Patel1, R Scott Leslie1, Patrick Thiebaud1, Michael B Nichol2, Simon SK Tang3, Henry Solomon3, Dennis Honda3, JoAnne M Foody41MedImpact Healthcare Systems, Inc., San Diego, CA, USA (Patrick Thiebaud was an employee of MedImpact Healthcare Systems,
Bimal V Patel, R Scott Leslie, Patrick Thiebaud, Michael B Nichol, Simon SK Tang, et al   +5 more
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