Results 71 to 80 of about 47,470 (225)

Hypertension [PDF]

, 2004
Hypertension is a rapidly moving clinical field with frequent developments in new pharmacologic agents and management strategies. Perhaps more importantly, there have been substantial improvements in our understanding of how best to use the drugs ...
Farrugia, Emanuel
core  

Insights from a six‐year hair drug analysis compendium in drug‐facilitated crimes involving vulnerable population cases

Journal of Forensic Sciences, EarlyView.
Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort, Coralie Boudin, Hélène Eysseric‐Guerin, Virginie Scolan, François Paysant, Cloé Scherpereel, Mélissa Revet, Françoise Stanke‐Labesque, Théo Willeman   +8 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Risk of Acute Infections in New Users of Antihypertensive Drugs: An Observational Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Functional inhibitors of acid sphingomyelinase enhance human immune function in vitro. We compared the risk of acute infection in users of amlodipine, a functional inhibitor of acid sphingomyelinase, to users of other first‐line ...
Noah Aebi, Christoph R. Meier, Susan S. Jick, Undine Lang, Julia Spoendlin   +4 more
doaj   +1 more source

Discharge after acute kidney injury : recognising and managing risk [PDF]

, 2016
Peer reviewedPublisher ...
Black, Corri, Marks, Angharad, Sawhney, Simon   +2 more
core  

Metabolism of the dihydropyridine calcium channel blockers mebudipine and dibudipine by isolated rat hepatocytes [PDF]

The prototype 1,4-dihydropyridine (1,4-DHP) nifedipine, indicated for the management of hypertension and angina pectoris, has drawbacks of rapid onset of vasodilating action and a short half-life.
Baarnhielm, Beresford, Borchard, Kobayashi, Mahmoudian, Mahmoudian, Mohri, Moldeus, Ramsch, Roden, Scherling, Scherling, Scherling, Stopher, Teramura, Van Zwieten   +15 more
core   +1 more source

Quantum chemistry calculation aided design of chiral ionic liquid-based extraction system for amlodipine separation [PDF]

, 2018
Amlodipine is a widely used medication in treating hypertension, which is also known as a chiral compound. So far efforts have been made to obtain optically pure (S)-amlodipine because (R)-amlodipine has poor efficacy and is ...
Becke, Bhattacharyya, Boys, Cao, Cui, Dong, Fileti, Fileti, Frisch, Fumio, Gong, Gotrane, Grimme, Holbach, Kapnissi-Christodoulou, Keith, Kimaru, Latosińska, Lee, Lee, Meng, Meredith, Parr, Peng, Po, Schuur, Sesin, Sun, Sun, Sunsandee, Tang, Tang, Tang, Tao, Wang, Wu, Wu, Xie, Xing, Yang, Yang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao   +48 more
core   +1 more source

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

British Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig, Yusuf C. Erdoğan, Benjamin Gottschalk, Michael Gruber, Andrea Groselj‐Strele, Sandra Burgstaller, Wolfgang F. Graier, Roland Malli   +7 more
wiley   +1 more source

The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle

Diabetic Medicine, EarlyView.
Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye, Ibi Erekosima, Adrian H. Heald, Gesiye Bozimo, Simon G. Anderson, Samuel Seidu, Kariba Akhidue, Adaeze Ugwu, Chioma Unachukwu, Ibitrokoemi Korubo, Kingsley Chukwuemeka Patrick‐Iwuanyanwu, Victoria Gomba, Uwoma Batubo, Victoria Akanatei, Victor Ken‐Uba, Iyeopu Siminialayi, Sokiprim Akoko, Justin Ideozu, Hamilton Opurum   +18 more
wiley   +1 more source

Protective Effects of Amlodipine Pretreatment on Contrast-Induced Acute Kidney Injury And Overall Survival In Hypertensive Patients

Frontiers in Pharmacology, 2020
BackgroudContrast-induced acute kidney injury (CI-AKI) is the most common adverse reaction caused by contrast media, which has been reported to prolong hospitalization and increase mortality and morbidity.
Wen-jun Yin, Ling-yun Zhou, Dai-yang Li, Yue-liang Xie, Jiang-lin Wang, Shan-ru Zuo, Kun Liu, Can Hu, Ge Zhou, Lin-hua Chen, Hui-qing Yang, Xiao-cong Zuo, Xiao-cong Zuo   +12 more
doaj   +1 more source