Results 121 to 130 of about 63,497 (263)

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Unravelling the Properties of Fluorescent Ammonium Salts to Obtain Thixotropic Hydrogels with Antitumoral Activity. [PDF]

ACS Omega
Billeci F, Buttacavoli M, Peri E, Marullo S, Cancemi P, D'Anna F.   +5 more
europepmc   +1 more source

Enantioselective β-Selective Addition of Isoxazolidin-5-ones to Allenoates Catalyzed by Quaternary Ammonium Salts. [PDF]

Synthesis (Stuttg), 2023
Zebrowski P, Röser K, Chrenko D, Pospíšil J, Waser M.   +4 more
europepmc   +1 more source

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source

Markovnikov-Selective Hydroboration of Aryl Alkenes Catalyzed by Quaternary Ammonium Salts. [PDF]

J Am Chem Soc
Huninik P, Im H, Szyling J, Baik MH, Walkowiak J.   +4 more
europepmc   +1 more source

Anti-Fouling and Anti-Biofilm Performance of Self-Polishing Waterborne Polyurethane with Gemini Quaternary Ammonium Salts. [PDF]

Polymers (Basel), 2023
Zhang Y, Ge T, Li Y, Lu J, Du H, Yan L, Tan H, Li J, Yin Y.   +8 more
europepmc   +1 more source

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

Advanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung, Alexander Beer, Susmita Ghosh, Ekaterina Pylaeva, Belal Alshaar, Tobias Tertel, Nils Bastian Leimkühler, Thomas Schroeder, Janine Gronewold, Nina Hagemann, Ayan Mohamud Yusuf, Benedikt Frank, Yiqiao Zhang, Dennis Nagel, Kim Schloeßer, Laura Karsch, Emily Hedtfeld, Sabrina Lohmann, Kathrin Blank, Andreas Kraus, Max Krumbein, Nastassia Kabankova, Hongxiao Wang, Almke Bader, Mathis Richter, Fengjun Zhang, Raphael Chevre, Bernd Giebel, Stephan Lang, Anika Grüneboom, Daniela Maier‐Begandt, Anja Hasenberg, Oliver Soehnlein, Hans Christian Reinhardt, Sven Heiles, Jianxu Chen, Jadwiga Jablonska, Albert Sickmann, Dirk M. Hermann, Matthias Gunzer   +39 more
wiley   +1 more source

A machine learning approach for predicting osmotic coefficients and deriving activity coefficients in alkyl ammonium salts. [PDF]

Sci Rep
Chawuthai R, Murathathunyaluk S, Saengsuradech S, Nukaew A, Simasatitkul L, Amornraksa S, Assabumrungrat S, Anantpinijwatna A.   +7 more
europepmc   +1 more source

Synthesis and Antimicrobial Evaluation of Bis-morpholine Triazine Quaternary Ammonium Salts. [PDF]

ChemMedChem, 2021
Morandini A, Leonetti B, Riello P, Sole R, Gatto V, Caligiuri I, Rizzolio F, Beghetto V.   +7 more
europepmc   +1 more source

Coupled Electronic and Ionic Conductivity in Strain‐Stiffening Hydrogels

Advanced Science, EarlyView.
A soft PVA–PABA hydrogel is developed that couples tissue‐like strain‐stiffening mechanics with dual ionic–electronic conduction. Dynamic boronic crosslinks enable self‐assembled percolative pathways, producing deformation‐responsive resistance with a stabilization plateau at stiffening onset, revealing alignment‐assisted charge transport and advancing
Md Al Raihan, Mark M. A. Mikhail, Khaled M. Hijazi, Hessameddin Yaghoobi, John P. Frampton, Vahid Adibnia, Michael S. Freund   +6 more
wiley   +1 more source