Results 171 to 180 of about 3,188 (257)

Long‐term safety and immunogenicity of ABvac40 active immunotherapy in mild cognitive impairment and very mild Alzheimer's disease: Results from AB1601 phase 2 extension study

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION ABvac40 is an active immunotherapy targeting Aβ40, the main component of cerebrovascular deposition in Alzheimer's disease (AD). A 24‐month randomized, placebo‐controlled phase 2 study (Part A) showed favorable safety and robust immunogenicity, with exploratory signals of clinical efficacy.
María Pascual‐Lucas, Ana María Lacosta, María Montañés, Jesús Canudas, Jorge Loscos, Inmaculada Monleón, José Antonio Allué, Leticia Sarasa, Noelia Fandos, Judith Romero, Manuel Sarasa, Mireia Torres, Dermot Whyms, Jose Terencio, Gerard Piñol‐Ripoll, Mercè Boada   +15 more
wiley   +1 more source

A prevention approach to undocumented forms of migration across the Mediterranean Sea: a critical assessment from Italy. [PDF]

Open Res Eur
Massari M, Miceli S, Ingrascì O.
europepmc   +1 more source

Plasma GFAP modifies the association of depressive symptoms with cognitive function: A population‐based study

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Late‐life depression is associated with cognitive impairment, but the underlying neural basis remains to be elucidated. We investigated the role of Alzheimer's disease (AD)–related plasma biomarkers in the depression–cognition association. METHODS Baseline data from 11,059 community‐dwelling older adults in the Alzheimer's Disease
Shuai Chen, Fengyu Wang, Yuxiang Jiao, Yuxin Niu, Kai Ma, Shuang He, Shenghui Wang, Rong Li, Siyuan Liu, Ying Zhao, Chenhong Li, Xiao Liu, Yaru Lu, Xiaodi Hao, Pan Du, Yibin Hao, Jiewen Zhang   +16 more
wiley   +1 more source

Infectious Diseases and Antimicrobial Resistance in the Gaza Strip: Epidemiological Drivers, Health System Disruptions, and Global Implications: A Narrative Review. [PDF]

Health Sci Rep
Farhadi N, Yarahmadi A, Afkhami H.
europepmc   +1 more source

Efficacy and Evidence Certainty of High‐Frequency rTMS for Cognitive Impairment Across Neuropsychiatric Disorders: An Umbrella Review

Brain and Behavior, Volume 16, Issue 8, August 2026.
This umbrella review of 29 meta‐analyses found that HF‐rTMS significantly improves cognition in Alzheimer's disease and vascular cognitive impairment. However, GRADE shows that most evidence is of low‐to‐very‐low certainty, and AMSTAR‐2 rates over 60% of reviews as critically low quality. Well‐designed trials are urgently needed.
Lin‐ling Wu, Xin‐cheng Huang, Juan‐juan Bi, Pei‐yuan He   +3 more
wiley   +1 more source

Evidence for the Induction of Anxiolytic‐Like Behavior and Memory Preservation by (+)‐Dihydrocarvone Through Studies in Adult Zebrafish and In Sílico

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
(+)‐Dihydrocarvone exhibited anxiolytic‐like and memory‐preserving effects in adult zebrafish. Behavioral assays showed reduced anxiety and improved cognitive performance, while in silico docking revealed strong interactions with GABAergic and cholinergic targets. These findings suggest (+)‐dihydrocarvone as a promising neuroactive compound for anxiety
Isadora Freitas de Sousa, Francisco Rogênio da Silva Mendes, Maria Kueirislene Amâncio Ferreira, Antônio Wlisses da Silva, Leticia Souza da Silva, Jane Eire Silva de Alencar Menezes, Márcia Machado Marinho, Emmanuel Silva Marinho, Matheus Nunes da Rocha, Antônio César Honorato Barreto, Alexandre Magno Rodrigues Teixeira, Hélcio Silva dos Santos   +11 more
wiley   +1 more source

Active Vaccination Strategies for Alzheimer's Disease: An Expanded Review

European Journal of Immunology, Volume 56, Issue 8, August 2026.
Overview of immunotherapeutic strategies targeting Alzheimer's disease (AD) pathology and their clinical implications. (Left) Key neuropathological hallmarks of AD, including extracellular amyloid‐beta (Aβ) aggregates and intraneuronal hyperphosphorylated Tau (phospho‐Tau), converge to produce synaptic failure, neuroinflammation and neuronal ...
Antonella Comitato, Antonino Neri, Andrea Cossarizza   +2 more
wiley   +1 more source

"I don't think of it as a shelter. I say I'm going home": a qualitative evaluation of a low-threshold shelter for women who use drugs. [PDF]

Harm Reduct J
Beaugard CA, Khudairi F, Yesufu O, Farina A, Laks J.   +4 more
europepmc   +1 more source

Collective Grievance Promotes Collective Action and Aggressive Intergroup Inclinations Through Dehumanization Among Conservative Members of Dominant Groups

European Journal of Social Psychology, Volume 56, Issue 5, Page 959-978, August 2026.
ABSTRACT Previous research has focused on disadvantaged groups seeking social change, overlooking how dominant groups mobilize to preserve the status quo. Across three studies (two correlational, one experimental), we explored how collective grievance—the feeling of being or having been collectively wronged by an outgroup—drives system‐preserving ...
Beatriz Alba, Alexandra Vázquez
wiley   +1 more source