Hemophilia A: An Ideal Disease for Prenatal Therapy
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source
Exiting the ground state: the broad spectrum of cell fates accessible from naïve human pluripotent stem cells. [PDF]
Park KM, Yin R, Theunissen TW.
europepmc +1 more source
WCN25-191 MULTI-OMICS ANALYSIS REVEALS PLASMA BIOMARKER CANDIDATES FOR CALCIFIC UREMIC ARTERIOLOPATHY PATIENTS TREATED WITH HUMAN AMNION-DERIVED MESENCHYMAL STEM CELLS [PDF]
Xiaoxue Ye +14 more
openalex +1 more source
Formyl-Methionyl-Leucyl-Phenylalanine Induces Prostaglandin E2 Release from Human Amnion-Derived WISH Cells by Phospholipase C-Mediated [Ca2+]i Rise1 [PDF]
Carla Biondi +5 more
openalex +1 more source
Global Delivery of Foetal Sequencing: Do We Need Some Standardisation?
ABSTRACT Objective The development of sequencing technologies has resulted in rapid expansion in the testing available for foetuses with structural anomalies to diagnose monogenic disorders. To understand the variability in how foetal sequencing services are delivered, we developed a survey that focussed on the scope of testing, any parallel testing ...
Natalie J. Chandler, Zandra C. Deans
wiley +1 more source
Distinct miRNA profiles in human amniotic tissue and its vesicular and non-vesicular secretome. [PDF]
Chaves-Solano N +12 more
europepmc +1 more source
Human Relaxin in the Amnion, Chorion, Decidua Parietalis, Basal Plate, and Placental Trophoblast by Immunocytochemistry and Northern Analysis* [PDF]
Vannara Sakbun +3 more
openalex +1 more source
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear +7 more
wiley +1 more source
Correction: Bioproduction, characterization, anticancer and antioxidant activities of extracellular melanin pigment produced by newly isolated microbial cell factories Streptomyces glaucescens NEAE-H. [PDF]
El-Naggar NE, El-Ewasy SM.
europepmc +1 more source

