Results 61 to 70 of about 78,165 (161)

Non‐Invasive Prenatal Diagnosis of Haemoglobinopathies: From Concept to Clinical Reality

Prenatal Diagnosis, EarlyView.
ABSTRACT Haemoglobinopathies are the most prevalent monogenic disorders worldwide, contributing significantly to childhood morbidity and mortality. Preventive strategies, including carrier screening and prenatal diagnosis, have successfully reduced disease incidence in regions with established programmes.
Irene Leonidou, Leila Sallie, Morgan Jean Bell‐Ricketts, Alexandros Abdel Massih, Lisa Joy Kaiser, Ashley Hoi Kiu Wong, María Teresa Martín Monreal, Panicos Shangaris   +7 more
wiley   +1 more source

Microbial Culture Profiles Following Fetal Surgery Versus Spontaneous Preterm Prelabor Rupture of Membranes in Multifetal Gestations

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To assess microbial culture profiles and antibiotic resistance patterns in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) following fetal surgery compared with spontaneous PPROM without fetal surgery. Method This retrospective cross‐sectional study included women with multiple pregnancies and PPROMs < 34 ...
Ohad Houri, Kinneret Tenenbaum Gavish, Bar Narkis, Ofir Sternfeld, Yael Haring, Eran Hadar, David Danon, Ana Idelson, Nir‐Ram Duvdevani, Yuval Gielchinsky   +9 more
wiley   +1 more source

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola, Aislinn O'Kane, Michael Heathman, Hannah Marotta, Hayley Trussel, Bobbie Ray, Shelley Dowden, Andrea R. Masters, David M. Haas, Sara K. Quinney   +9 more
wiley   +1 more source

Reading between the lesions: Recognizing intent in pediatric burn injuries

Journal of Forensic Sciences, EarlyView.
Abstract Burn injuries are common in childhood and may occur in accidental or non‐accidental circumstances, making forensic interpretation challenging. Evaluation is difficult when clinical findings, reported history, and contextual evidence are incomplete or discordant.
Alice Buzzelli, Alberto Amadasi, Lorenzo Franceschetti, Valentina Bugelli   +3 more
wiley   +1 more source

Optic nerve hypoplasia and septo‐optic‐pituitary dysplasia

Developmental Medicine &Child Neurology, EarlyView.
Optic nerve hypoplasia and septo‐optic‐pituitary dysplasia. Abstract The presence of a small optic disc on funduscopy is prerequisite for the diagnosis of optic nerve hypoplasia (ONH). Visual acuity may be normal. However, amblyopia can occur in ONH. A relative afferent pupillary light defect indicates unilateral or asymmetrical ONH.
Michael S. Salman
wiley   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Red‐Complex Bacterial DNA in Carotid Atheroma of Dentate and Long‐Term Edentulous Patients and Its Association With Mitochondrial DNA Copy Number

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to evaluate (i) the presence of red complex bacteria in carotid atheroma plaques of dentate and edentulous patients and (ii) the possible relationship between mitochondrial DNA copy number (mtDNA‐cn), an indicator of mitochondrial function, and periodontal disease.
Ayşe Toraman, Ebru Sağlam, Emine Toraman, Serkan Ketenciler, Serhat Köseoğlu   +4 more
wiley   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

A Case of Amniotic Band Sequence Complicated by Severe Skeletal Malocclusion

, 2015
This clinical report describes the management of a patient who was diagnosed with amniotic band sequence (ABS) complicated with severe skeletal malocclusion, associated with severe muscle weakness.
Sayaka Yoshiba, Tetsutaro Yamaguchi, S. Ohtsuka, T. Shirota   +3 more
semanticscholar   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source