Results 171 to 180 of about 2,227,658 (392)

Therapeutic potential of amniotic-fluid-derived stem cells on liver fibrosis model in mice

, 2014
Shao-Yu Peng, Chih-Jen Chou, Po‐Jen Cheng, I-Chen Ko, Yi-Jung Kao, Yu‐Hsu Chen, Winston T. K. Cheng, Steven W. Shaw, Shinn‐Chih Wu   +8 more
openalex   +1 more source

Automatic Respiratory and Bulk Patient Motion Corrected 3D Fetal MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT PurposeTo develop a framework (ACROBATIC) for correcting motion in 3D radial fetal MRI. MethodsData were simulated (N = 200) and acquired in utero (N = 11, gestational age: 32 ± 2 weeks). Motion due to maternal respiration was estimated by extracting a self‐gating signal and applying focused navigation.
Robin Ferincz, Leonor Alamo, Aurelio Secinaro, Estelle Tenisch, Aurélien Bustin, Davide Piccini, Milan Prša, Jérôme Yerly, Christopher W. Roy   +8 more
wiley   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

131. Presence of a Specific AAV-Neutralizing IgG in Human Amniotic Fluid

, 2002

openalex   +1 more source

Oct-4-expressing cells in human amniotic fluid: a new source for stem cell research? [PDF]

, 2003
Andrea‐Romana Prusa
openalex   +1 more source

Global Delivery of Foetal Sequencing: Do We Need Some Standardisation?

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective The development of sequencing technologies has resulted in rapid expansion in the testing available for foetuses with structural anomalies to diagnose monogenic disorders. To understand the variability in how foetal sequencing services are delivered, we developed a survey that focussed on the scope of testing, any parallel testing ...
Natalie J. Chandler, Zandra C. Deans
wiley   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Amniotic Fluid Stem Cells from EGFP Transgenic Mice Attenuate Hyperoxia-Induced Acute Lung Injury

, 2013
Shih-Tao Wen, Wei Chen, Hsiao‐Ling Chen, Cheng‐Wei Lai, Chih‐Ching Yen, Kun‐Hsiung Lee, Shinn‐Chih Wu, Chuan‐Mu Chen   +7 more
openalex   +2 more sources

Prenatal Exome Sequencing Analysis in Fetuses With Structural Anomalies: A Multicenter Prospective Cohort Study With Practical Implications

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate the diagnostic value of prenatal exome sequencing (ES) integrated with copy number variant (CNV) and single nucleotide variant (SNV) analysis (ES‐CNV/SNV) in fetuses with structural anomalies following negative chromosomal microarray analysis (CMA) and karyotyping, and to delineate the practical challenges encountered ...
Yulin Jiang, Haibo Li, Xiangyu Zhu, Liangpu Xu, Ying Chang, Fengqun Dong, Jianping Xiao, Jian Gao, Minyue Dong, Ying Peng, Hua Jin, Ting Wang, Xiaoxiao Xie, Lin Zhang, Hongmei Zhuang, Na Hao, Xiya Zhou, Hongna Wang, Ying You, Kun Ma, Rui Xiao, Qingwei Qi   +21 more
wiley   +1 more source