Results 31 to 40 of about 55,609 (256)

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Development and Validation of a Rodent Model of Amniotic Fluid Exchange: A Prospective Laboratory-Based Study

Clinical and Experimental Obstetrics & Gynecology
Background: Significant interplay exists between the amniotic fluid and the developing fetus. However the true nature of the relationship between the amniotic fluid and the fetus, as well as the fetal membranes, is very poorly understood due to the lack ...
Braxton Forde, Samuel Martin, Jose L. Peiro   +2 more
doaj   +1 more source

Presence of parabens, phenols and phthalates in paired maternal serum, urine and amniotic fluid

Environment International, 2022
Objective: To examine whether selected endocrine disrupting chemicals were present in pregnant women and passed through the placental barrier to amniotic fluid, potentially exposing the developing fetus.
Elvira V. Bräuner, Cecilie S. Uldbjerg, Youn-Hee Lim, Laura S. Gregersen, Marianna Krause, Hanne Frederiksen, Anna-Maria Andersson   +6 more
doaj   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Amniotic and cervical fluids progranulin levels in pregnancies complicated by spontaneous preterm delivery with respect to intra-amniotic complications—a retrospective cohort study

Scientific Reports
The main aim of the study was to determine progranulin levels in amniotic and cervical fluid samples from pregnancies complicated by preterm prelabor rupture of membranes (PPROM) or preterm labor with intact membranes (PTL), with concomitant microbial ...
Ondrej Soucek, Marian Kacerovsky, Ivana Musilova, Rudolf Kukla, Radka Bolehovska, Pavel Bostik, Bo Jacobsson, Ctirad Andrys   +7 more
doaj   +1 more source

Amniotic fluid disorders and the effects on prenatal outcome: a retrospective cohort study

BMC Pregnancy and Childbirth, 2021
Background The amniotic fluid is a protective liquid present in the amniotic sac. Two types of amniotic fluid disorders have been identified. First refers to polyhydramnios, which is an immoderate volume of amniotic fluid with an Amniotic Fluid Index ...
H. Bakhsh, H. Alenizy, S. Alenazi, S. Alnasser, N. Alanazi, M. Alsowinea, L. Alharbi, B. Alfaifi   +7 more
doaj   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

RNA Sequencing Reveals Diverse Functions of Amniotic Fluid Neutrophils and Monocytes/Macrophages in Intra-Amniotic Infection

Journal of Innate Immunity, 2020
Intra-amniotic infection, the invasion of microbes into the amniotic cavity resulting in inflammation, is a clinical condition that can lead to adverse pregnancy outcomes for the mother and fetus as well as severe long-term neonatal morbidities.
Nardhy Gomez-Lopez, Roberto Romero, Aneesha Varrey, Yaozhu Leng, Derek Miller, Bogdan Done, Yi Xu, Gaurav Bhatti, Kenichiro Motomura, Meyer Gershater, Roger Pique-Regi, Adi L. Tarca   +11 more
doaj   +1 more source

A Novel Splice Variant in ERGIC1 Causes Arthrogryposis Multiplex Congenita—Characterization Using Urine‐Derived Cells

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is defined as the presence of joint contractures affecting at least two body regions at birth. Three different ERGIC1 variants have been reported in individuals with AMC. Here, we report on a 16‐year‐old male with a homozygous ERGIC1 c.250+1G>A variant that was classified as a variant of uncertain ...
Lauren Kerr, Paul McKay, Juliana Marulanda, Zenghui Wu, Reggie Hamdy, Sena Tavukcu, Noémi Dahan‐Oliel, Frank Rauch   +7 more
wiley   +1 more source

Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor.

PLoS ONE, 2020
ObjectiveAmniotic fluid cytokines have been implicated in the mechanisms of preterm labor and birth. Cytokines can be packaged within or on the surface of extracellular vesicles.
Gaurav Bhatti, Roberto Romero, Gregory Edward Rice, Wendy Fitzgerald, Percy Pacora, Nardhy Gomez-Lopez, Mahendra Kavdia, Adi L Tarca, Leonid Margolis   +8 more
doaj   +1 more source