Results 121 to 130 of about 9,447,029 (203)

Disorders in Amniotic Fluid

open access: yes, 2007
Disorders in amniotic fluid production occur frequently in pregnancy, and are associated with increased perinatal mortality and morbidity. This article will discuss amniotic fluid physiology, and will summarize noninvasive methods of measuring amniotic ...
Lynnae K Sauvage
core   +1 more source

Human placental transfer of xenobiotics in health and disease: New approach methodologies for developmental and reproductive toxicology testing and mathematical modelling

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend New approach methodologies (NAMs) to test the pharmaco‐ and chemicokinetics of compound transfer across the human placental barrier in late pregnancy. Abstract This review addresses an important and timely topic at the intersection of placental biology with respect to barrier transfer kinetics, toxicology and mathematical ...
Paul Brownbill, Eleanor Doman
wiley   +1 more source

Physiological and anatomical determinants of placental drug transfer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis   +3 more
wiley   +1 more source

Too Much of a Good Thing: Updated Current Management and Perinatal Outcomes of Polyhydramnios

open access: yesJournal of Medical Ultrasound
Amniotic fluid assessment is crucial in prenatal ultrasound to monitor fetal conditions, with polyhydramnios, characterized by excessive amniotic fluid, affecting 1%–2% of pregnancies. Polyhydramnios is linked to complications such as placental abruption,
Fang-Tzu Wu, Chih-Ping Chen
doaj   +1 more source

Ascending infection of Gardnerella spp. and compartmentalized inflammatory response in fetal–maternal interface organ‐on‐chip model

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The fetal–maternal interface organ‐on‐chip was used to investigate the ascending infection of Gardnerella spp. across the decidua (DEC), chorion trophoblast (CTC), amnion mesenchymal (AMC) and amnion epithelial (AEC) compartments over 48 h.
Mariana de Castro Silva   +7 more
wiley   +1 more source

Ovine fetal adaptations to chronically reduced urine flow: preservation of amniotic fluid volume

open access: yes, 1996
Mann, Stephanie E., Mark J. M. Nijland, and Michael G. Ross.Ovine fetal adaptations to chronically reduced urine flow: preservation of amniotic fluid volume. J. Appl. Physiol.
Mark J. M. Nijland   +2 more
core   +1 more source

Exploring the Passive Second Stage of Labour and Related Perinatal Outcomes in a Physiological Cohort

open access: yesBirth, Volume 53, Issue 4, Page 721-730, December 2026.
ABSTRACT Background The passive second stage of labor has been increasingly recognized as a normal phase of labor. However, it remains poorly studied, especially in healthy women. This study aims to assess the passive phase in healthy laboring women and maternal and neonatal outcomes.
Lucia Zagra   +6 more
wiley   +1 more source

A New Case of Lethal Congenital Contracture Syndrome Type 3 With Hyperinsulinism and Optic Atrophy

open access: yesClinical Genetics, Volume 110, Issue 6, Page 736-741, December 2026.
PIP5K1C‐related lethal congenital contracture syndrome with hyperinsulinism and optic atrophy. ABSTRACT Lethal congenital contracture syndrome 3 (LCCS3, MIM #611369) is a rare autosomal recessive neuromuscular disorder caused by biallelic loss‐of‐function (LOF) variants in PIP5K1C, reported in only two families to date.
Tameemi Abdalla Moady   +3 more
wiley   +1 more source

Latency following preterm prelabor rupture of membranes before 34 weeks of gestation and its association with perinatal outcomes: a retrospective cohort study

open access: yesArchives of Gynecology and Obstetrics
Purpose To evaluate the association between latency duration and perinatal outcomes in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) before 34 weeks of gestation, and to assess the role of gestational age at PPROM and amniotic ...
Pilar López-Martínez   +10 more
doaj   +1 more source

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