Results 121 to 130 of about 6,898 (170)
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Immunogenicity of Amodiaquine in the Rat
International Archives of Allergy and Applied Immunology, 2009Amodiaquine is an antimalarial drug that has been associated with adverse reactions which may be immune mediated. Specific IgG anti-amodiaquine antibodies were detected after administration of the drug to rats (269 μmol/kg for 4 days), using an enzyme-linked immunosorbent assay employing amodiaquine conjugated to metallothionein as an antigen.
J B, Clarke +3 more
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Archives of Ophthalmology, 1982
A 34-year-old man ingested more then 250 g of amodiaquine hydrochloride (for pain) during one year and was noted to have diffuse conjunctival, corneal, and skin changes and also abnormal results from retinal function tests. Ultrastructural examination of corneal and conjunctival biopsy specimens revealed intralysosomal membranous and amorphous ...
L W, Hirst +4 more
openaire +2 more sources
A 34-year-old man ingested more then 250 g of amodiaquine hydrochloride (for pain) during one year and was noted to have diffuse conjunctival, corneal, and skin changes and also abnormal results from retinal function tests. Ultrastructural examination of corneal and conjunctival biopsy specimens revealed intralysosomal membranous and amorphous ...
L W, Hirst +4 more
openaire +2 more sources
Life Sciences, 1985
Existing analytical methods for assaying the 4-aminoquinoline antimalarial amodiaquine in body fluids are nonspecific and obscure the fact that little or no amodiaquine is present in the blood of dosed persons. We have isolated four metabolites of amodiaquine. The two major metabolites have been identified; one is desethylamodiaquine, and the other has
F C, Churchill +5 more
openaire +2 more sources
Existing analytical methods for assaying the 4-aminoquinoline antimalarial amodiaquine in body fluids are nonspecific and obscure the fact that little or no amodiaquine is present in the blood of dosed persons. We have isolated four metabolites of amodiaquine. The two major metabolites have been identified; one is desethylamodiaquine, and the other has
F C, Churchill +5 more
openaire +2 more sources
Clinical and In Vitro Resistance of Plasmodium falciparum to Artesunate-Amodiaquine in Cambodia
Clinical Infectious Diseases, 2021Melissa Mairet-Khedim +2 more
exaly
Medecine tropicale : revue du Corps de sante colonial, 2008
Amodiaquin is still considered as a poorly tolerated antimalarial causing hematological and hepatic toxicity. In view of complications observed during prophylaxis, the WHO has advised against the use of amodiaquin for prophylaxis as well as treatment.
openaire +1 more source
Amodiaquin is still considered as a poorly tolerated antimalarial causing hematological and hepatic toxicity. In view of complications observed during prophylaxis, the WHO has advised against the use of amodiaquin for prophylaxis as well as treatment.
openaire +1 more source

