Results 251 to 260 of about 17,783 (291)

Recent Advances in the Treatment of Malaria. [PDF]

Pharmaceutics
Alghamdi JM, Al-Qahtani AA, Alhamlan FS, Al-Qahtani AA.   +3 more
europepmc   +1 more source

Impact of dhps mutations on sulfadoxine-pyrimethamine protective efficacy and implications for malaria chemoprevention. [PDF]

Nat Commun
Mousa A, Cuomo-Dannenburg G, Thompson HA, Bell DJ, D'Alessandro U, Gosling R, Nahum A, Barnes KI, Raman J, Workmann L, Foo YS, Flegg JA, Hocke EF, Hansson H, Chopo-Pizarro A, Beshir KB, Alifrangis M, Chico RM, Sutherland CJ, Okell LC, Roper C.   +20 more
europepmc   +1 more source

The spread of molecular markers of artemisinin partial resistance and diagnostic evasion in Eritrea: a retrospective molecular epidemiology study.

Lancet Microbe
Mihreteab S, Anderson K, Fuente IM, Sutherland CJ, Smith D, Cunningham J, Beshir KB, Cheng Q.   +7 more
europepmc   +1 more source

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AMODIAQUINE AGRANULOCYTOSIS

Medical Journal of Australia, 1977
A case of profound neutropenia and severe infection after the administration of amodiaquine is presented. The recommended dose for malaria prophylaxis was administered.
P, Gillespie, F, Wagner
openaire   +2 more sources

Amodiaquine Ocular Changes

Archives of Ophthalmology, 1982
A 34-year-old man ingested more then 250 g of amodiaquine hydrochloride (for pain) during one year and was noted to have diffuse conjunctival, corneal, and skin changes and also abnormal results from retinal function tests. Ultrastructural examination of corneal and conjunctival biopsy specimens revealed intralysosomal membranous and amorphous ...
W. Richard Green, George E. Sanborn, Neil R. Miller, William D. Heath, Lawrence W. Hirst   +4 more
openaire   +2 more sources

Amodiaquine as a prodrug: Importance of metabolite(s) in the antimalarial effect of amodiaquine in humans

Life Sciences, 1985
Existing analytical methods for assaying the 4-aminoquinoline antimalarial amodiaquine in body fluids are nonspecific and obscure the fact that little or no amodiaquine is present in the blood of dosed persons. We have isolated four metabolites of amodiaquine. The two major metabolites have been identified; one is desethylamodiaquine, and the other has
Ira K. Schwartz, Leslie C. Patchen, Carlos C. Campbell, Phuc Nguyen-Dinh, Frederick C. Churchill, Charlotte M. Dickinson   +5 more
openaire   +3 more sources

Immunogenicity of Amodiaquine in the Rat

International Archives of Allergy and Immunology, 1990
Amodiaquine is an antimalarial drug that has been associated with adverse reactions which may be immune mediated. Specific IgG anti-amodiaquine antibodies were detected after administration of the drug to rats (269 μmol/kg for 4 days), using an enzyme-linked immunosorbent assay employing amodiaquine conjugated to metallothionein as an antigen.
J.B. Clarke, B.K. Park, Neil R. Kitteringham, J.L. Maggs   +3 more
openaire   +3 more sources