Results 181 to 190 of about 18,481 (259)

Direct and indirect costs associated with declining distance visual acuity: A nationwide longitudinal cost‐of‐illness study with 11‐year follow‐up

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine the direct and indirect costs associated with declining distance visual acuity (VA). Methods A longitudinal approach was applied to a large, nationally representative sample with extensive data, including VA measured at two time points.
Joonas Taipale, Petri Purola, Janika Nättinen, Saku Väätäinen, Seppo Koskinen, Hannu Uusitalo   +5 more
wiley   +1 more source

Delivery of nano‐formulated drugs to solid tumours is selectively increased by co‐application of the vascular disrupting agent CA4P

British Journal of Pharmacology, EarlyView.
Background and purpose Nano‐formulated chemotherapeutics prolong systemic availability of drugs and can reduce systemic toxicity, but their accumulation in solid tumours is often limited and unpredictable. Broadly applicable strategies to selectively enhance tumour delivery are lacking.
Annabel Kitowski, Constanze Heise, Stefanie Sperling, Jasmin Hotz, Danica Bajic, Marina Rubey, Kathrin Klar, Georg Höfner, Julien Vollaire, Veronique Josserand, Jean‐Luc Coll, Oliver Thorn‐Seshold, Petar Marinković, Julia Thorn‐Seshold   +13 more
wiley   +1 more source

School‐to‐Work Transitions Among Out‐of‐Home Care and Aftercare Experienced Individuals: A Norwegian National Register Study

Child &Family Social Work, EarlyView.
ABSTRACT Individuals with child protection service (CPS) experience face increased risks of social exclusion and unemployment. Employment is vital for both financial stability and health. Teenagers in out‐of‐home care (OHC) are particularly vulnerable to unemployment.
Trine Holten, Kirsti Klem Valset
wiley   +1 more source

Comprehensive Assessment of the KDM2B‐Associated Neurodevelopmental Disorder and the 12q24.31 Microdeletion Syndrome

Clinical Genetics, EarlyView.
We set out to characterize genotype–phenotype correlations in the recently delineated KDM2B‐associated neurodevelopmental disorder. We observe a highly penetrant CxxC domain‐related phenotype with distinct facial features supported by GestaltMatcher. In contrast, our findings point to variable expressivity and incomplete penetrance of loss‐of‐function ...
Amber S. E. van Oirsouw, Tzung‐Chien Hsieh, Martijn Koetsier, Abdulrazak Alali, Fatimah Albuainain, Elena Bacchelli, Tahsin Stefan Barakat, Yline Capri, Sandra Chantot‐Bastaraud, Valeria Capra, Deanna Alexis Carere, Emma Clement, Nour Elkhateeb, Madeleine Franchi, Jing‐Mei Li, Nicole Matthews, Vanda McNiven, Sarju G. Mehta, Masayuki Nakamura, Chanika Phornphutkul, Nicole Revencu, Marcello Scala, Natalie Shallow, Jennifer Stefanich, Marta Viggiano, Paola Visconti, Susan Walker, Federico Zara, Mariëlle Alders, Bobby P. C. Koeleman, Renske Oegema   +30 more
wiley   +1 more source

ReTrace: Interactive Visualizations for Reasoning Traces of Large Reasoning Models

Computer Graphics Forum, EarlyView.
Abstract Recent advances in Large Language Models have led to Large Reasoning Models, which produce step‐by‐step reasoning traces. Such traces may offer insight into how models think, improving explainability and clarifying the underlying process. These traces, however, are often verbose and complex, making them cognitively demanding to comprehend ...
L. Felder, J. Miller, M. Wallinger, S. G. Kobourov, C. Chen   +4 more
wiley   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

Cell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang, Qizhi Wang, Yu Wu, Chen Gu, Mingfei Li, Yong Fan, Xiangjin Kang, Lei Li, Zheng Gao, Mingyan Hei, Jianqiao Liu, Lei Li   +11 more
wiley   +1 more source

Understanding the Relationship of Humanity to God and to Creation Through God's Love: Tuomo Mannermaa's New Interpretation of Martin Luther's View of the Two Kinds of Love

Dialog, EarlyView.
ABSTRACT Based on Luther's twenty‐eighth thesis in the Heidelberg Disputation, which contrasts God's love and human love, Tuomo Mannermaa offers a detailed analysis of the theme of love in Luther's theology, highlighting its paradoxical character. According to Mannermaa's interpretation, Luther insists that God's love and human love move in opposite ...
Ying Yang, Paulos Z. Z. Huang
wiley   +1 more source

Moving hens into cages affects cognitive performance, extinction learning and motivation for rewards. [PDF]

Anim Welf
Calderón-Amor J, Lecorps B, Ávila R, Tadich T.   +3 more
europepmc   +1 more source

Emerging Risk: Intranasal Tin Exacerbates Allergic Rhinitis in Humans and Mice

Allergy, EarlyView.
Delgama A. S. M. Nishadhi, Shogo Sumiya, Akira Tazaki, Takumi Kagawa, Mohamed Abdelmoneim, Masafumi Sakashita, Kazuhiro Ogi, Shigeharu Fujieda, Shinichi Iwasaki, Masashi Kato   +9 more
wiley   +1 more source

Investigating the Incremental Cost and Utilization Burden of Obstructive Sleep Apnea in Overweight to Severely Obese Patients

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To quantify the incremental economic and utilization burden of comorbid obstructive sleep apnea (OSA) within an overweight to severely obese adult population. Material and Methods This retrospective cohort study utilized 2016–2025 IQVIA PharMetrics Plus Closed Health Plan commercial claims data to identify overweight to severely obese ...
Hyung Seok John Kim, Tien Hoang Tran, Christopher N. Schmickl, Julia F. Slejko   +3 more
wiley   +1 more source