Results 11 to 20 of about 21,140 (76)
Molecular Characterization of AmpC β-lactamases in Enterobacteriaceae [PDF]
, 2022 AmpC β-lactamases are enzymes that are resistant to β-lactams, such as penicillin and cephalosporin, but not cefoxitin and cefotetan. This study was conducted to characterize AmpC β-lactamases in Enterobacteriaceae.
Chitralekha Saikumar, D. Bindu
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Ceftriaxone-resistant salmonella enterica serotype Newport, France. [PDF]
, 2008 The multidrug-resistant (MDR) Salmonella enterica serotype Newport strain that produces CMY-2 beta-lactamase (Newport MDR-AmpC) was the source of sporadic cases and outbreaks in humans in France during 2000-2005.
Delauné, Aurélia +30 more
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AMPc – Sinalização Intracelular [PDF]
, 2016 O software é disponibilizado gratuitamente, entretanto é necessário que o usuário efetue cadastro no site onde o software está hospedado. O software requer a instalação do plug-in Flash PlayerEste software apresenta um modelo computacional que explora ...
Yokaichiya, Daniela +2 more
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Probing the Role of Asn 152 in the Class C β-lactamase AmpC [PDF]
, 2012 AmpC, a class C β-lactamase, is a main cause of antibiotic resistance to cephalosporins in many species of bacteria. The current proposed mechanism of action involves an acyl-intermediate, where the enzyme becomes covalently attached to the drug at ...
Powers, Rachel +4 more
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, 1994 浓香型大曲酒质量的优劣，取决于酒体中己酸乙酯含量的高低，而在生产发酵过程中，酯的形成比较缓慢，因而生产周期长;成本高。该项目从大曲中分离德育出一株活性高而稳定的酯化酶生产菌株，由该菌株生产粗酶制剂，方法简单易行。将该酶制剂应用于生产，可缩短发酵期1/3，优质酒率提高10个百分点，而且可提高己酸乙酯含量，成效显著。现已建成年产酯化酶粗酶制剂1000吨，高酯调味酒100吨的生产线，经试生产工艺合理，运行正常，操作方便，产品的产量与质量均达到设计要求。与传统工艺相比，可缩短发酵周期3/4～2/3 ...
core
, 1995 浓香型大曲酒质量的优劣，取决于酒体中己酸乙酯含量的高低，而在生产发酵过程中，酯的形成比较缓慢，因而生产周期长;成本高。该项目从大曲中分离德育出一株活性高而稳定的酯化酶生产菌株，由该菌株生产粗酶制剂，方法简单易行。将该酶制剂应用于生产，可缩短发酵期1/3，优质酒率提高10个百分点，而且可提高己酸乙酯含量，成效显著。现已建成年产酯化酶粗酶制剂1000吨，高酯调味酒100吨的生产线，经试生产工艺合理，运行正常，操作方便，产品的产量与质量均达到设计要求。与传统工艺相比，可缩短发酵周期3/4～2/3 ...
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, 2016 聚酮化合物是由细菌、真菌、植物等产生的次级代谢产物，具有多种生物活性，广泛应用于人类生产生活中。聚酮结构一般较为复杂且常具有多个手性中心，化学合成困难，目前主要通过微生物发酵获得。阐明聚酮生物合成机制，是聚酮化合物研究的重要内容。酰基辅酶A（coenzyme A，CoA）如丙酰CoA、乙酰CoA、丙二酰CoA以及甲基丙二酰CoA等是聚酮生物合成的前体，但商品化产品种类较少且往往价格昂贵，严重限制聚酮生物合成的体外研究。酰基CoA合成酶可以催化羧酸与CoA缩合，为聚酮的生物合成提供前体 ...
董爽爽
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, 2016 【目的】为寻找能合成丙酰辅酶A和丁酰辅酶A等聚酮合成前体的生物催化剂,用体外酶学实验对一个酯酰辅酶A合成酶进行了表征。【方法】利用丙二酰辅酶A合成酶作为输入序列,通过BLAST程序在Caldicellulosiruptor owensensis OL的基因组中找到1个酯酰辅酶A合成酶基因。在大肠杆菌中进行了异源表达,并通过亲和层析进行纯化。底物谱、最适反应条件、稳定性和动力学参数通过体外酶学实验进行表征,而定点突变则用于活性中心的氨基酸残基的分析。【结果】该酶具有较好的底物宽泛性,可识别丙酸、丁酸 ...
郑舰艇 +3 more
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The β-lactamase inhibitor avibactam (NXL104) does not induce ampC β -lactamase in Enterobacter cloacae [PDF]
, 2013 Christine Miossec, Monique Claudon, Premavathy Levasseur, Michael T Black Novexel, Romainville, France Abstract: Induction of ampC β-lactamase expression can often compromise antibiotic treatment and is triggered by several β-lactams (such as ...
Black MT +3 more
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AMPc – Sinalização Intracelular [PDF]
O software é disponibilizado gratuitamente, entretanto é necessário que o usuário efetue cadastro no site onde o software está hospedado. O software requer a instalação do plug-in Flash PlayerEste software apresenta um modelo computacional que explora ...
Yokaichiya, Daniela +2 more
core +2 more sources