Results 81 to 90 of about 35,400 (107)

Risk Analysis Implications of Dose-Response Thresholds for NLRP3 Inflammasome-Mediated Diseases: Respirable Crystalline Silica and Lung Cancer as an Example

Dose-Response, 2019
Chronic inflammation mediates an extraordinarily wide range of diseases. Recent progress in understanding intracellular inflammasome assembly, priming, activation, cytokine signaling, and interactions with mitochondrial reactive oxygen species, lysosome ...
Louis Anthony (Tony) Cox
doaj   +1 more source

The Effect of Joint and Several Liability on the Bankruptcy Rate of Defendants: Evidence from Asbestos Ligation [PDF]

The Effect of Joint and Several Liability on the Bankruptcy Rate of Defendants: Evidence from Asbestos Litigation - Under the doctrine of joint and several liability, if two defendants jointly share a liability and the first becomes insolvent, his unpaid
Anup Malani
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Comparison of various methodological approaches to model asbestos thresholds for mesothelioma

Frontiers in Public Health
BackgroundThere is evidence to support several modes of action (MoAs), and particularly non-genotoxic MoAs, for mesothelioma induced by asbestiform elongate mineral particles (EMPs).
Julie E. Goodman, Andrey Korchevskiy, Ann G. Wylie   +2 more
doaj   +1 more source

J Immunotoxicol [PDF]

Exposure to amphibole asbestos has been associated with production of autoantibodies in mice and humans, and increases the risk of systemic autoimmune disease. However, epidemiological studies of chrysotile exposure have not indicated a similar induction

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Mesothelin methylation, soluble mesothelin related protein levels and inflammation profiling in workers chronically exposed to naturally occurring asbestos fibers

Translational Oncology
Exposure to asbestiform fibers, including chrysotile and amphibole, is carcinogenic, causing malignant pleural mesothelioma (MPM) when inhaled. Some populations globally face Naturally Occurring Asbestos (NOA) exposure, leading to MPM cases like in ...
Caterina Ledda, Carla Loreto, Claudia Lombardo, Venera Cardile, Venerando Rapisarda   +4 more
doaj   +1 more source

Autoimmun Rev

A growing body of evidence supports an association between systemic autoimmune disease and exposure to amphibole asbestos, a form of asbestos typically with straight, stiff, needle-like fibers that are easily inhaled.

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Chemical characterization and reactivity of iron chelator-treated amphibole asbestos

, 1997
Iron in amphibole asbestos is implicated in the pathogenicity of inhaled fibers. Evidence includes the observation that iron chelators can suppress fiber-induced tissue damage.
Fubini, B,, Krozer, A,, Amandusson, H,, Kasemo, B,, Ericsson, T,, Gold, J,, Zanetti, G,   +6 more
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Comparative analysis of asbestos body and fiber content in formalin-fixed vs. paraffin-embedded lung tissue

Frontiers in Public Health
IntroductionAsbestos body and fiber burdens may be determined using different preparations of lung tissue. Paraffin-embedded tissue requires more complex steps than formalin-fixed tissue.
Barbara K. Kuhn, Bart Vrugt, Bart Vrugt, Alex Low, Julie E. Goodman, Richard Attanoos   +5 more
doaj   +1 more source

Habit of elongate amphibole particles as a predictor of mesothelial carcinogenicity

Toxicology Reports
Introduction: Amphiboles are a class of minerals that are abundantly present in the environment. Amphiboles may exist in several habits, with asbestiform particles behaving like typical amphibole asbestos and non-asbestiform (or massive) reported to be ...
Andrey A. Korchevskiy, Ann G. Wylie
doaj   +1 more source

[Letter from Alex Bradford to Asbestos Magazine - December 2, 1944]

, 1944
Letter from Alex Bradford to Asbestos Magazine hoping to receive a list of possible western or mid-western manufacturers of asbestos fire-fighting suits and ...
Bradford, Alex
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