Results 151 to 160 of about 107,290 (304)

Reversible, Chemically Gated FRET via Ligand‐Activated Acceptors

open access: yesAdvanced Science, EarlyView.
Fluorogen binding turns the compact FAST tag into a tunable FRET acceptor, with ligand chemistry programming spectral overlap and excited‐state lifetimes. Fluorescence‐lifetime imaging reads out energy transfer through the shortened donor lifetime, while simply adding or washing out the dye switches FRET on and off, reversibly mapping the supramodular ...
Nivedita Singh   +7 more
wiley   +1 more source

CAFCA: a Novel Tool for the Calculation of Amphiphilic Properties of Charged Drug Molecules

open access: yesCHIMIA, 2000
Amphiphilic compounds play crucial roles in biology. They represent molecules with an inherent tendency to orient themselves in a suitable environment (e.g. a lipid bilayer).
Holger Fischer   +2 more
doaj  

Water‐Soluble Luminescent Trityl Radical for Fluorescence/Magnetic Resonance Dual‐Modal Imaging Probe

open access: yesAdvanced Science, EarlyView.
Stable water‐soluble luminescent tris(2,4,6‐trichlorophenyl)methyl (TTM) radicals, TTM‐trisTP3B and TTM‐trisTP9B, were designed and successfully synthesized. They exhibited deep‐red emissions and high photostability in water. TTM‐trisTP3B exhibited dual functionality as a fluorescence imaging (FI) probe and a magnetic resonance imaging (MRI) contrast ...
Kosuke Anraku   +6 more
wiley   +1 more source

Zinc Fingers as Programmable Metalloprotein Scaffolds for Altering Pathogenic Biomolecular Phase Transitions

open access: yesAdvanced Science, EarlyView.
Modular zinc finger (ZF) metalloproteins function as programmable biomolecular scaffolds that modulate pathogenic amyloid assembly. Through direct protein–protein interactions, ZF arrays alter amyloid phase behavior and redirect β‐sheet fibrillization toward nontoxic aggregates.
Seongmin Park   +16 more
wiley   +1 more source

amphiphile

open access: yes
Citation: 'amphiphile' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13795 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Functional MXene Inks for Printed Electronics: Chemistry, Rheology, and Devices

open access: yesAdvanced Science, EarlyView.
Functional MXene inks are emerging as building blocks for MXetronics, connecting MXene synthesis, surface functionalization, ink formulation, and advanced printing with device‐level applications. This review maps how composition, stability, rheology, and processability govern printed structures and enable high‐performance sensors, energy‐storage ...
Shahzaib Ali   +6 more
wiley   +1 more source

In Situ Bioorthogonal Synthesis of PROTACs via Dual‐Responsive Cleavage for Synergistic Photo‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian   +14 more
wiley   +1 more source

Carbon nanotubes self-assembled by amphiphilic peptide -helices

open access: yes, 2003
Carbon nanotubes self-assembled by amphiphilic peptide ...
A Ortiz-Acevedo (13693756)   +8 more
core  

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

open access: yesAdvanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He   +6 more
wiley   +1 more source

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