Results 51 to 60 of about 107,290 (304)

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Synthesis of Amphiphilic Triblock Copolymers by ATRP and Coalescence Suppression Effect in Suspension Polymerization

Journal of Chemical Engineering of Japan, 2023
In this study, the role of amphiphilic triblock copolymers in suppressing the coalescence of the polymers obtained by suspension polymerization was systematically investigated through the preparation of polymer beads using a common monomer (methyl ...
Eri Fujita, Kosuke Kaneko, Tsubasa Oshima, Daiki Fujioka, Kimiyoshi Kaneko, Kiyomi Fuchigami, Tomonori Hanasaki   +6 more
doaj   +1 more source

The amphiphilic character of glycogenin [PDF]

FEBS Letters, 2001
This study describes for the first time the amphiphilicity of the protein moiety of proteoglycogen. Glycogenin but not proteoglycogen associates to phospholipid vesicles and forms by itself stable Gibbs and Langmuir monolayers at the air–buffer interface.
Carrizo, Marı́a E, Miozzo, Marı́a C, Maggio, Bruno, Curtino, Juan A   +3 more
openaire   +2 more sources

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

New strategies for the synthesis of amphiphilic networks.

, 1999
Amphiphilic and hydrogel polymers are useful biomedical materials. This paper presents some recent work on new syntheses of such materials. Amphiphilic gels have been prepared by the Diels–Alder reaction of poly(ethylene glycol)s that contain acetylene ...
Rimmer, S., Fullwood, Nigel J., N. Fullwood, P. Tattersall, S. Rimmer, J.R. Ebdon, Tattersall, P., Ebdon, J. R.   +7 more
core   +4 more sources

A Candidate for Multitopic Probes for Ligand Discovery in Dynamic Combinatorial Chemistry

Molecules, 2019
Multifunctionalized materials are expected to be versatile probes to find specific interactions between a ligand and a target biomaterial. Thus, efficient methods to prepare possible combinations of the functionalities is desired.
Keiko Yoneyama, Rina Suzuki, Yusuke Kuramochi, Akiharu Satake   +3 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Ultrasonic desulfurization of amphiphilic magnetic-Janus nanosheets in oil-water mixture system

Ultrasonics Sonochemistry, 2021
Fe3O4 was obtained by reacting FeCl2 and FeCl3 with polyethylene glycol, and labeled onto a amphiphilic Janus nanosheet. It was confirmed by infrared spectroscopy, SEM, AFM and EDS that the Fe3O4 nanoparticles changed from hydrophilic to amphiphilic. The
Chunwei Shi, Xue Zhang, Xiaoyan Zhang, Ping Chen, Lingzi Xu   +4 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Oxidation of Benzyl Alcohols to Carbonyl Compounds Catalyzed by Reusable Manganese Porphyrin under Mild Aqueous Conditions [PDF]

Iranian Journal of Chemistry & Chemical Engineering
The main aim of this study is to introduce a new catalytic system referred to as p(NaAMPS-co-AN)‐[Mn(TMPyP)], which is a combination of poly[(2‐acrylamido-2-methyl-1-propane sulfonic acid-co-acrylonitrile)-Mn(III) meso tetra(N-methyl-4-pyridyl) porphine.
Zahra Sokhandan, Massomeh Ghorbanloo, Tahereh Mokary Yazdely   +2 more
doaj   +1 more source