Results 221 to 230 of about 13,097,347 (378)

Cetuximab plus 5‐fluorouracil in patients with advanced cutaneous squamous cell carcinoma: a retrospective cohort study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background For patients with locally advanced (la) or metastatic (m) cutaneous squamous cell carcinoma (cSCC) who are not candidates for curative surgery/radiation or systemic anti‐PD1 therapy, anti‐EGFR in combination with chemotherapy is a rational treatment option.
Julia Huynh, Thomas Eigentler, Rose K. C. Moritz, Gabriela Poch, Max Schlaak, Gabor Dobos   +5 more
wiley   +1 more source

In vitro and in vivo evaluation of the leishmanicidal and cytotoxic activities of chitosan and chitosan-amphotericin B. [PDF]

AMB Express
Mousavi P, Rahimi Esboei B, Pourhajibagher M, Zolfaghari A, Shahmoradi Z, Namdar F, Ahmadi S, Mousavi SM, Parandin F, Hejazi SH.   +9 more
europepmc   +1 more source

A phosphoserine phosphatase variant present in the brain of Alzheimer's disease patients favors nuclear mistargeting

The FEBS Journal, EarlyView.
l‐serine levels in the human brain are maintained by the phosphorylated pathway, a three‐step process catalyzed by phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase (PSAT) and phosphoserine phosphatase (PSP). These enzymes assemble in a metabolon called the serinosome. The double R27S/D32G PSP variant was identified in the brain of
Silvia Sacchi, Valeria Buoli Comani, Ivan Arisi, Francesco Marchesani, Valentina Rabattoni, Omar De Bei, Zoraide Motta, Alessio Peracchi, Stefano Bruno, Loredano Pollegioni, Barbara Campanini   +10 more
wiley   +1 more source

Comparison of Early Fungicidal Activity and Mortality Between Daily Liposomal Amphotericin B and Daily Amphotericin B Deoxycholate for Cryptococcal Meningitis. [PDF]

Clin Infect Dis
Kimuda S, Kwizera R, Dai B, Kigozi E, Kasozi D, Rutakingirwa MK, Tukundane A, Shifah N, Luggya T, Luswata A, Ndyetukira JF, Yueh SL, Mulwana S, Wele A, Bahr NC, Meya DB, Boulware DR, Skipper CP.   +17 more
europepmc   +1 more source

TSC22D1 is a newly identified inhibitor of insulin secretion in pancreatic beta cells

The FEBS Journal, EarlyView.
TSC22D1 acts downstream of glucose signaling and negatively regulates insulin secretion in pancreatic beta cells. Mechanistically, TSC22D1 interacts with FoxO1. Elevated glucose levels enhance the TSC22D1–FoxO1 interaction indirectly by increasing the protein abundance of TSC22D1. Importantly, TSC22D1 and FoxO1 not only physically associate but also co‐
Sümbül Yıldırım, Amit Mhamane, Svenja Lösch, Annika Wieder, Ezgi Ermis, Ann‐Christine König, Sevgican Yilmaz, Stefanie M. Hauck, Fatih Kocabas, Julia Szendroedi, Stephan Herzig, Bilgen Ekim   +11 more
wiley   +1 more source

Anti-biofilm peptides can rescue fluconazole and amphotericin B efficacies against Candida albicans. [PDF]

Sci Rep
Kissmann AK, Mildenberger V, Krämer M, Alpízar-Pedraza D, Martell-Huguet EM, Perez-Erviti JA, Cetinkaya A, Pietrasik J, Otero-Gonzalez AJ, Firacative C, Rodríguez A, Ständker L, Weil T, Stenger S, Rosenau F.   +14 more
europepmc   +1 more source

Synergistic antifungal activity and reduced toxicity of liposomal amphotericin B combined with gramicidin S or NF [PDF]

, 1987
Roy L. Hopfer, R T Mehta, Gabriel López-Berestein   +2 more
openalex   +1 more source

Activation of G protein‐coupled parathyroid hormone receptors in rat incisor odontoblasts promotes mineralization via cyclic adenosine monophosphate, not Ca2+ signalling: In vitro study

International Endodontic Journal, EarlyView.
Abstract Aim Parathyroid hormone (PTH) and its Gαs‐coupled receptors, PTH receptor, mediate odontoblast differentiation; however, the detailed intracellular adenylyl cyclase‐mediated signalling pathway mediated by the PTH–PTH receptor axis remains to be elucidated. Therefore, we measured the intracellular levels of cyclic adenosine monophosphate (cAMP)
Natsuki Saito, Takehito Ouchi, Maki Kimura, Ryuya Kurashima, Yoshiyuki Shibukawa   +4 more
wiley   +1 more source

Antifungal effects of andrographolide and its combination with amphotericin B against selected fungal pathogens. [PDF]

PeerJ
Dafur GS, Tuan Kub TN, Banga Singh KK, Harun A, Lambuk F, Mohamud R, Kadir R, Ismail N, Yusop N.   +8 more
europepmc   +1 more source

Inhibition of Coccidioides immitis In Vitro and Enhancement of Anticoccidioidal Effects of Amphotericin B by Polymyxin B

, 1975
Michael Collins, D. Pappagianis
openalex   +1 more source