Results 301 to 310 of about 13,097,347 (378)

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity

Drug Testing and Analysis, Volume 17, Issue 7, Page 1118-1130, July 2025.
Waxy‐ or putty‐like materials has emerged as a novel drug preparation for synthetic cannabinoids and other drugs in UK prisons. An in vitro CB1 bioassay was used to evaluate the CB1 activating potential of MDMB‐INACA and extracts from eight seized samples. MDMB‐INACA had moderate efficacy but low potency at CB1.
Axelle Timmerman, Marie H. Deventer, Rachael Andrews, Robert Reid, Victoria Marland, Darren Edwards, Christopher R. Pudney, Niamh Nic Daéid, Christophe P. Stove, Caitlyn Norman   +9 more
wiley   +1 more source

Amine-Functionalized Graphene Quantum Dots Conjugated with Amphotericin B: Synthesis, Characterization, and In Vitro Evaluation for Visceral Leishmaniasis Treatment. [PDF]

ACS Omega
Madhukar P, Kesarwani R, Pandey S, Singh VK, Rao Gedda M, Singh OP, Shaz M, Kumar R, Sundar S.   +8 more
europepmc   +1 more source

Preclinical Testing of 3D Printed, Cell Loaded Hydrogel Based Corneal Substitutes on Rabbit Model

Macromolecular Bioscience, Volume 25, Issue 7, July 2025.
This study reports on 3D‐printed methacrylated gelatin (GelMA) implants designed to serve as corneal stroma substitutes. The implants are characterized for their transparency, mechanical strength, and cytocompatibility. In vivo tests on rabbits demonstrate successful integration, with histopathological analysis showing tissue regeneration, appropriate ...
Deniz Basoz, Aslihan Akalinli, Senem Buyuksungur, A. R. Cenk Celebi, Deniz Yucel, Nesrin Hasirci, Vasif Hasirci   +6 more
wiley   +1 more source

Synthesis and Chemical Characterization of Chloroquine, Hydroxychloroquine, Zinc, and Cinnamic Acid Organocomplexes: Potential Drug Candidates for SARS‐CoV‐2 Treatment and Microbial Control

ChemistrySelect, Volume 10, Issue 27, July 18, 2025.
Zn‐quinolines were synthesized with high yields of 78% and 85%. The study focuses on drug repositioning to improve properties and reduce toxicity for COVID‐19 treatment. New Zn‐based compounds demonstrated antiviral and antimicrobial activities with low toxicity.
Carla Peron, Paulo Roberto dos Santos, João Pedro de Oliveira Mezzomo, Fernando Joel Scariot, Ariel Maia, Laura Calle Gonzalez, Deise do Nascimento de Freitas, Ana Paula Longaray Delamare, Pablo Machado, Ana Paula Duarte de Souza, Sidnei Moura   +10 more
wiley   +1 more source

Successful Treatment of Bladder Fungus Ball Due to <i>Candida auris</i> With Systemic/Local Amphotericin B and Surgical Excision. [PDF]

Case Rep Pediatr
Erkol Yilmaz Y, Havan M, Eyduran E, Penezoğlu N, Öcal D, Teber S, Çiftçi E, Soygür YT, Kendirli T.   +8 more
europepmc   +1 more source

Tunable Release of Ions from Graphene Oxide Laminates for Sustained Antibacterial Activity in a Biomimetic Environment

Small, Volume 21, Issue 28, July 17, 2025.
A slow and longer‐term delivery of silver ions for sustained antimicrobial activity is developed by incorporating silver ions within the 2D nanocapillaries of GO laminates. The controlled release of silver ions from these laminates has provided sustained antimicrobial activity for more than 10 days in a biomimetic environment.
Swathi Suran, Negin Kamyar, Kun Huang, Farzad Foroutan, Premlal Balakrishna Pillai, Xuzhao Liu, John Vaughan, Darren Wilson, Philip J. Day, Rahul R. Nair   +9 more
wiley   +1 more source

Genome alteration of Leishmania orientalis under Amphotericin B inhibiting conditions. [PDF]

PLoS Negl Trop Dis
Anuntasomboon P, Siripattanapipong S, Unajak S, Choowongkomon K, Burchmore R, Leelayoova S, Mungthin M, E-Kobon T.   +7 more
europepmc   +1 more source

In vivo activation of macrophage oxidative burst activity by cytokines and amphotericin B

, 1990
J. E. Wolf, S E Massof
openalex   +1 more source

Fluorescent Antibiotics: Bridging Diagnostic and Therapy in the Fight against Bacterial Infections

Small Science, Volume 5, Issue 7, July 2025.
This review critically evaluates fluorescent antibiotics as promising agents combining diagnostic precision with therapeutic efficacy. It highlights advances in probe design, chemical conjugation strategies, real‐time imaging applications, selective pathogen detection, and targeted therapy. The potential to combat antimicrobial resistance is discussed,
Tan Phuoc Ton, Richard Bright, Vi Khanh Truong, Krasimir Vasilev   +3 more
wiley   +1 more source

iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis. [PDF]

Front Microbiol
Zhao J, Fang W, Gao Y, Chen J, Wang G, Gu J.   +5 more
europepmc   +1 more source