Results 101 to 110 of about 78,152 (269)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Applications of the genetic algorithm optimisation approach in the design of high efficiency microwave class E power amplifiers [PDF]

open access: yes
In this thesis Genetic Algorithm Optimisation Methods (GA) is studied and for the first time used to design high efficiency microwave class E power amplifiers (PAs) and associated load patch antennas.
Lu, Qing
core  

Operational Amplifiers [PDF]

open access: yes, 2005
25cm ...
Clayton,George
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Contribuição ao estudo do impacto das não linearidades nos sistemas de telecomunicações [PDF]

open access: yes, 2007
Doutoramento em Engenharia ElectrotécnicaEsta tese insere-se na área de Electrónica de Rádio Frequência e Microondas e visa o desenvolvimento de ferramentas que permitam a melhor compreensão e análise do impacto da distorção não linear produzida em ...
Lavrador, Pedro Miguel Ribeiro
core   +1 more source

Transmission systems with low noise phase sensitive parametric amplifiers [PDF]

open access: yes, 2015
We review and present the recent research on phase-sensititve amplifiers, and describe how they can be used in transmission ...
Karlsson, Magnus   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

High Efficiency Power Amplifier Based on Envelope Elimination and Restoration Technique [PDF]

open access: yes, 2010
Due to complex envelope and phase modulation employed in modern transmitters it is necessary to use power amplifiers that have high linearity. Linear power amplifiers (classes A, B and AB) are commonly used, but they suffer from low efficiency especially
Alou Cervera, Pedro   +9 more
core   +1 more source

12b 500MS/s successive‐approximation‐register‐assisted pipeline analogue‐to‐digital convertor using a four‐stage ring amplifier with coarse‐analogue‐to‐digital convertor embedded

open access: yesElectronics Letters
This article presents a 12b 500MS/s successive‐approximation‐register‐assisted pipeline analogue‐to‐digital converter. By adopting a new auto‐zero scheme, a calibration‐free four‐stage ring residue amplifier with a small offset cancellation capacitor is ...
Linghao Liu, Junyan Ren, Fan Ye
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy