ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
High gain and wideband hybrid optical amplifier using bismuth-doped and neodymium-doped fibers for E-band applications. [PDF]
Donodin A, Kiani L, Noor S, Forysiak W.
europepmc +1 more source
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen +7 more
wiley +1 more source
Development of a High-Frequency, High-Temperature Class-A Amplifier Based on a Silicon Carbide Static Induction Transistor. [PDF]
Scardelletti MC, Grgat JR, Zorman CA.
europepmc +1 more source
Electronic Noise Measurement of a Magnetoresistive Sensor: A Comparative Study. [PDF]
Davidaș C +5 more
europepmc +1 more source
Design and Measured Assessment of a MOS-Only, Capacitorless, Miniature 64-Channel Headstage Circuit for High-Density Surface Electromyography. [PDF]
Koutsoftidis S +6 more
europepmc +1 more source
Per-Span Microwave-Frequency Fiber Interferometry for Amplified Transmission Links Employing High-Loss Loopbacks. [PDF]
Karydis GA +6 more
europepmc +1 more source
"Hantavirus at sea: Why cruise ships must be ready for animal-borne disease." [PDF]
Ahmed NS +4 more
europepmc +1 more source
Reinforcing measles control in the Americas amid mass gatherings: detection, response, and traveler health implications. [PDF]
Pan American Health Organization.
europepmc +1 more source

