Results 101 to 110 of about 159,814 (309)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Covert Communications in a Hybrid DF/AF Relay System

open access: yesSensors
In this paper, we study covert communications in a hybrid decode-and-forward (DF)/ amplify-and-forward (AF) relay system. The considered relay in normal operation forwards messages from a source node to a destination node in either DF or AF mode on ...
Jihwan Moon
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Efficient Simulation of the Outage Probability of Multihop Systems

open access: yesIEEE Photonics Journal, 2017
In this paper, we present an efficient importance sampling estimator for the evaluation of the outage probability of multihop systems with amplify-and-forward channel state-information-assisted. The proposed estimator is endowed with the bounded relative
Chaouki Ben Issaid   +2 more
doaj   +1 more source

Cooperative Terrestrial-Underwater Wireless Optical Links by Using an Amplify-and-Forward Strategy. [PDF]

open access: yesSensors (Basel), 2022
Jurado-Navas A   +3 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Towards the Optimal Amplify-and-Forward Cooperative Diversity Scheme

open access: yes, 2006
In a slow fading channel, how to find a cooperative diversity scheme that achieves the transmit diversity bound is still an open problem. In fact, all previously proposed amplify-and-forward (AF) and decode-and-forward (DF) schemes do not improve with ...
Belfiore, Jean-Claude, Yang, Sheng
core   +3 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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