Results 71 to 80 of about 148,329 (294)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Interference Channel With Full-Duplex Amplify-and-Forward Transmitter Cooperations
IEEE Access, 2019 This paper considers a Gaussian interference channel (IC), where two transmitters send two messages to two receivers respectively. By utilizing the in-band full-duplex (FD) amplify-and-forward (AF) scheme, transmitter cooperations are deployed to enhance
Jianhao Huang, Dan Wang, Chuan Huang
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Ergodic capacity of the exponentially correlated slotted amplify and forward relay channel [PDF]
, 2012 In this paper we analyze the performance degradation of slotted amplify-and-forward protocol in wireless environments with high node density where the number of relays grows asymptotically large.
Widanagamage, Anushka +2 more
core
SINR Maximizing Beamforming Schemes for the Full Duplex Amplify-and-Forward Relay Channel
IEEE Access, 2017 We propose signal-to-interference-plus-noise power ratio (SINR) maximizing rank one beamforming schemes for the full-duplex (FD) relay systems. The non-regenerative amplify and forward (AaF) relay is considered with multiple transmit antennas and ...
Duckdong Hwang +2 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
ABUAD Journal of Engineering Research and DevelopmentWireless communication system is crucial to telecommunications infrastructure and has played an essential role in national growth. However, the system's performance is hindered by multipath propagation, which has negatively impact in its performance ...
Samson Iyanda OJO +4 more
doaj +1 more source