Results 41 to 50 of about 1,056,129 (315)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Study of a Welding Pool Harmonic Oscillations Influence on the Welded Metal Hardness and Weld Bead Width

Журнал інженерних наук, 2019
The comparison results of the hardness measuring of welded metal and the heat-affected zone of the eight welded beads from low-carbon steel obtained by surfacing CO2/MAG with welding bath oscillation influence at values of amplitude equaled 0.5 mm ...
Lebedev V. A., Solomiichuk T. G., Novykov S. V.   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Iterative amplitude/phase multiple-symbol differential sphere detection for DAPSK modulated transmissions

, 2012
Differentially encoded and non-coherently detected transceivers exhibit a low complexity, since they dispense with complex channel estimation. Albeit this is achieved at the cost of requiring an increased transmit power, they are particularly beneficial,
Hari, K.V.S., Wang, Li, Li Wang, K.V.S. Hari, Hanzo, Lajos, Lajos Hanzo   +5 more
core   +1 more source

Dual picosecond fast tunable optical parametric amplifier laser system for wide-field nonlinear optical microscopy

APL Photonics
In the last decades, nonlinear optical microscopy techniques, such as two-Photon Excited Fluorescence (2PEF), Sum Frequency Generation (SFG), and Hyperspectral Coherent Anti-Stokes Raman Scattering (H-CARS) microscopy, emerged as powerful tools to image ...
Federico Vernuccio, Assia Benachir, Eric Michele Fantuzzi, Benoit Morel, Simone Bux, Erwann Martin, José Villanueva, Yoann Pertot, Nicolas Thiré, Sandro Heuke, Hervé Rigneault   +10 more
doaj   +1 more source

Development of difference spectrophotometric method for the estimation of leflunomide in tablet dosage form [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2012
A new simple, accurate, precise, highly sensitive and reproducible difference spectrophotometric method for the determination of leflunomide in bulk and pharmaceutical dosage form is described. Difference spectroscopic method is based on the principle
Lakshmana Prabu S., Prakash Suriya T.N.K., Shanmugarathinam A.   +2 more
doaj   +1 more source

Physical Simulation of Ultrasonic Imaging Logging Response

Sensors, 2022
Ultrasonic imaging logging can visually identify the location, shape, dip angle and orientation of fractures and holes. The method has not been effectively applied in the field; one of the prime reasons is that the results of physical simulation ...
Junqiang Lu, Jiyong Han, Jinping Wu, Xiaohua Che, Wenxiao Qiao, Jiale Wang, Xu Chen   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Amplitude-frequency response of the RCVT transformation ratio.

, 2018
Amplitude-frequency response of the RCVT transformation ratio.
Jian Le (2832722), Chao Gao (154531), Hao Zhang (15339), Qian Zhou (125859)   +3 more
core   +1 more source

Femtosecond Laser Percussion Drilling of Silicon Using Repetitive Single Pulse, MHz-, and GHz-Burst Regimes

Micromachines
In this contribution, we present novel results on top-down drilling in silicon, the most important semiconductor material, focusing specifically on the influence of the laser parameters.
Pierre Balage, Manon Lafargue, Théo Guilberteau, Guillaume Bonamis, Clemens Hönninger, John Lopez, Inka Manek-Hönninger   +6 more
doaj   +1 more source