Results 51 to 60 of about 960,683 (280)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Stability Analysis and Internal Heating Effect on Oscillatory Convection in a Viscoelastic Fluid Saturated Porous Medium Under Gravity Modulation

International Journal of Applied Mechanics and Engineering, 2016
In this paper, we investigate the combined effect of internal heating and time periodic gravity modulation in a viscoelastic fluid saturated porous medium by reducing the problem into a complex non-autonomous Ginzgburg-Landau equation.
B.S. Bhadauria, M.K. Singh, A. Singh, B.K. Singh, P. Kiran   +4 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Electromigration-Induced Propagation of Nonlinear Surface Waves

, 2002
Due to the effects of surface electromigration, waves can propagate over the free surface of a current-carrying metallic or semiconducting film of thickness h_0.
A. Davey, A. V. Latyshev, B. M. Lake, G. G. Stokes, H. C. Yuen, H. Hasimoto, H.-C. Jeong, J. E. Sanchez, Jr., J. H. Rose, J. Krug, L. Shemer, M. Mahadevan, M. Mahadevan, M. Mahadevan, M. R. Gungor, M. R. Gungor, M. R. Gungor, M. Schimschak, M. Schimschak, N. Shimoni, N. Shimoni, O. Kraft, O. Kraft, P. G. Drazin, R. M. Bradley, R. Mark Bradley, S. Stoyanov, S. Stoyanov, T. B. Benjamin, T. B. Benjamin, V. E. Zakharov, V. E. Zakharov, W. Wang   +32 more
core   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Amplitude Equation for SPDEs with Quadratic Non-Linearities

Electronic Journal of Probability, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Blömker, Dirk, mohammed, Wael
openaire   +5 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

MAGNETO-ELASTIC PRINCIPAL RESONANCE OF AXIALLY MOVING FERROMAGNETIC PLATE UNDER HARMONIC MAGNETIC FORCE (MT)

Jixie qiangdu, 2023
Based on Hamilton principle, the nonlinear magneto-elastic vibration equation of ferromagnetic plate is established under the combined action of mechanical load and harmonic magnetic force induced by magnetization.
CAO TianXiao, HU YuDa
doaj  

Weakly Nonlinear Analysis of Electroconvection in a Suspended Fluid Film

, 1997
It has been experimentally observed that weakly conducting suspended films of smectic liquid crystals undergo electroconvection when subjected to a large enough potential difference.
I. Stakgold, L. Kramer, M. C. Cross, M. C. Cross, M. C. Cross, P. Manneville, S. Chandrasekhar, S. Faetti, S. Ried, S. S. Mao, S. W. Morris, S. W. Morris, Stephen W. Morris, V. B. Deyirmenjian, W. H. Press, Z. A. Daya, Zahir A. Daya   +16 more
core   +2 more sources

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source