Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
What Can Local Transfer Entropy Tell Us about Phase-Amplitude Coupling in Electrophysiological Signals? [PDF]
Modulation of the amplitude of high-frequency cortical field activity locked to changes in the phase of a slower brain rhythm is known as phase-amplitude coupling (PAC).
Martínez-Cancino, Ramón +12 more
core +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle +4 more
wiley +1 more source
The Vicentini sound archive of the Arena di Verona Foundation: A preservation and restoration project [PDF]
In the sound archive field, a long-term maintenance of the collective human memory in its original form is not sustainable. All physical carriers are subject to degradation and the information stored on such carriers is bound to vanish.
CANAZZA TARGON, SERGIO +8 more
core
Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park +7 more
wiley +1 more source
Correlation Between Involute Profile Waviness and Gear Transmission Performance
Involute tooth profile contains a lot of waviness information. Digging and expanding the application of waviness information to establish its relationship with gear transmission performance has important engineering value.
Zhou Yuansheng +3 more
doaj
On amplitude information carried by the ambient seismic field
The use of the ambient seismic field (ASF) to extract Earth's response has received significant attention in the last several years. Multiple studies demonstrate the utility of the ASF for estimating high-resolution velocity models in various locations. In this paper, we discuss the amplitude information carried by the ASF.
Prieto, German A. +3 more
openaire +1 more source
The preservation of amplitude information in burst phenomena in physiological recordings [PDF]
This paper describes an inexpensive and simple electronic circuit that rectifies and smooths high-frequency burst data and holds the peak value of the burst for predetermined time intervals.
F. James Doyle, Richard Allon
openaire +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source

