Results 131 to 140 of about 20,999 (278)
During the development of OA, elevated RORα in chondrocytes inhibits β‐catenin degradation in the cytoplasm by activating the Wnt/β‐catenin signaling pathway. When β‐catenin protein accumulates excessively in the cytoplasm, it is transferred to the nucleus and binds to the cytosolic TCF/LEF transcriptional complex, which activates downstream target ...
Ruijue Zhu +9 more
wiley +1 more source
Sentience in cephalopod molluscs: an updated assessment
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell +4 more
wiley +1 more source
ABSTRACT Stent‐related dissection is a well‐recognized complication of endovascular intervention. However, acute arterial occlusion resulting from stent‐induced intimal flap displacement at a major bifurcation is rare and carries a high risk of limb‐threatening ischemia.
Le Zhang +4 more
wiley +1 more source
We present a case of digital ischemia investigated and localized using point‐of‐care ultrasound (POCUS), in a patient that was subsrquently diagnosed with antiphospholipid syndrome and polycythemia vera concurrently, in the setting of active tobacco use. ABSTRACT In patients with undifferentiated extremity ischemia, point‐of‐care ultrasound (POCUS) can
Tristan Burgess +2 more
wiley +1 more source
The role of attachment in emotion regulation of traumatic stress
Recent research has shown that there is a positive relationship between insecure attachment and psychopathology (van IJzendoorn, Bakermans-Kranenburg & Juffer, 2008).
Arikan, Gizem
core
ABSTRACT Background Acute Limb Ischaemia (ALI) is a limb and life‐threatening condition that is often associated with cardiovascular disease, atrial fibrillation (AF), diabetes and smoking. It is less commonly associated with active malignancy. There is growing evidence regarding this association.
Amos Au, Audrey Choy, Ming Yii
wiley +1 more source
Long-Term Clinical and Radiologic Evaluation of Micronized Acellular Dermal Matrix-Assisted Reconstruction in Diabetes-Related and Traumatic Foot Wounds With Bone Defects. [PDF]
ABSTRACT To investigate whether micronized acellular dermal matrix (mADM) can be used to treat diabetes‐related and traumatic foot wounds with bone defects after bone or joint resection. We retrospectively reviewed 52 patients who underwent bone or joint resection, followed by mADM‐assisted reconstruction of diabetes‐related or traumatic foot wounds ...
Nam HJ, Bae J, Kim SY, Choi HJ.
europepmc +2 more sources
ABSTRACT Introduction Foot‐related conditions are a leading cause of all hospitalisations and amputations worldwide. Half of these foot‐related hospitalisations are in people without diabetes. Yet, few studies seem to have explored risk factors for foot‐related hospitalisations in populations with or without diabetes. This study aimed to systematically
Sucharitha R. Weerasuriya +5 more
wiley +1 more source
In Belize, a 7‐year nationwide study reveals a sharp rise in antimicrobial resistance in surgical infections. ESBL‐producing bacteria more than doubled to > 45%, with critical treatment gaps and geographic hotspots identified. Sentinel pan‐drug‐resistant cases and a correlation between antibiotic use and resistance underscore the urgent need for ...
Innocent E. Nwachukwu +5 more
wiley +1 more source
Phylogenetic Profiling of the Diabetic Foot Ulcer Microbiome of an Afro‐Caribbean Population
Illumina amplicon sequencing revealed diverse bacterial and fungal communities in chronic diabetic foot ulcers (DFUs) and adjacent normal skin from Afro‐Caribbean patients. Corynebacterium striatum dominated both sites. DFUs had higher relative abundance of Pseudomonas aeruginosa and the antifungal‐resistant Candida duobushaemulonii, with significantly
Nkemcho Ojeh +9 more
wiley +1 more source

