Results 91 to 100 of about 104,877 (268)

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

Risk Factors for Early Major Amputation in the First Diabetic Forefoot Amputation

open access: yesFoot & Ankle Orthopaedics
Category: Diabetes; Other Introduction/Purpose: Subsequent major amputations within 1 year after initial forefoot amputations are sometimes necessary when other options for saving the foot are unavailable.
JaeHyeon Seo MD   +3 more
doaj   +1 more source

Identification of Risk Factors and Survival in Patients Undergoing Re-amputation After Extremity Amputation

open access: yesCerrahpaşa Medical Journal
Objective: This study aimed to identify the risk factors contributing to re-amputation, survival rates, and mortality determinants in patients who underwent unilateral lower extremity amputation due to diabetes mellitus (DM) or peripheral artery disease
Cumhur Deniz Davulcu   +1 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Surgical approaches to canine appendicular osteosarcoma part 1- anatomic landmarks and amputation techniques

open access: yesFrontiers in Veterinary Science
Osteosarcoma (OSA) is the most common primary bone neoplasm affecting dogs and the appendicular bones are frequently affected, accounting for up to 80% of reported cases. After tumor diagnosis and staging, surgery followed by adjuvant chemotherapy is the
Ryshely Sonaly De Moura Borges   +7 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

open access: yesBMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang   +6 more
wiley   +1 more source

Inflammation and nutrition-derived indicators for predicting amputation risk in patients with type 2 diabetic foot ulcers

open access: yesFrontiers in Nutrition
BackgroundInflammation and malnutrition affect the prognosis of diabetic foot ulcers (DFU). This study systematically evaluated the impact and predictive value of inflammation and nutrition-derived indicators for amputation in DFU using machine learning ...
Junyu He   +5 more
doaj   +1 more source

Sequential catalytic nanosystem of carbon dots and uricase integrated with polydopamine for therapy of gouty wound ulceration

open access: yesBMEMat, EarlyView.
Sequential dual‐catalytic treatment of the gout wound ulceration process by CDs‐Uri@PDA. (a) Synthesis steps and morphology of CDs‐Uri@PDA. (b) Sequential treatment process and mechanism of CDs‐Uri@PDA for gout wound ulceration according to (i) uric acid reduction, (ii) antibacterial activity, and (iii) anti‐inflammatory effects.
Yonglan Yang   +11 more
wiley   +1 more source

Predictors of amputation in patients with acute compartment syndrome after tibial fracture: a nomogram prediction model

open access: yesJournal of Orthopaedic Surgery and Research
Purposes Amputation is a serious complication in patients with acute compartment syndrome (ACS). However, it risk factors are still poorly understood. Our study aims to investigate the risk factors of amputation in patients with ACS.
Tao Wang, Qi Zhang, Zhiyong Hou
doaj   +1 more source

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