Results 91 to 100 of about 216,547 (314)

Status of oncology drugs with a conditional approval: A cross‐sectional comparison of the Food and Drug Administration and Health Canada

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley   +1 more source

The phantom limb [PDF]

open access: yes, 1951
Thesis (M.D.)—Boston ...
Freed, Murray
core  

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

Surgical revascularization versus amputation for peripheral vascular disease in dialysis patients: a cohort study

open access: yesBMC Nephrology, 2005
Background Surgical treatment of peripheral vascular disease (PVD) in dialysis patients is controversial. Methods We examined the post-operative morbidity and mortality of surgical revascularization or amputation for PVD in a retrospective analysis of ...
Ramkumar Nirupama   +3 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Introduction to Prosthetic Limbs [PDF]

open access: yes, 2015
Approximately 2 million people in the Unites States alone have had an amputation, and many of these people use a prosthetic limb daily. The prosthetic limb, which began as a primitive device, is now a highly sophisticated piece of technology.
Ramos, Victoria
core   +1 more source

Impact of delayed amputation on clinical outcomes compared to that of early amputation in patients with blunt polytrauma

open access: yesScientific Reports
Delayed amputation after failed limb salvage can lead to negative clinical and functional outcomes due to complications, including re-amputation.
Jinjoo Kim   +3 more
doaj   +1 more source

Ontological theory for ontological engineering: Biomedical systems information integration [PDF]

open access: yes, 2004
Software application ontologies have the potential to become the keystone in state-of-the-art information management techniques. It is expected that these ontologies will support the sort of reasoning power required to navigate large and complex ...
Ceusters, Werner   +3 more
core   +1 more source

Evaluation of the Surgical and Pharmacological Treatment of Diabetic Foot Infection: A Retrospective Study [PDF]

open access: yes, 2017
BACKGROUND: Diabetic foot infection is a major cause of patient disabilities and lowers limb amputations, with high treatment costs and hospitalisation requirements.
Aliakbar, Adil Hassan   +2 more
core   +4 more sources

Marine silicon for biomedical sustainability

open access: yesBMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han   +3 more
wiley   +1 more source

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