Results 161 to 170 of about 104,877 (268)

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

The Sacred Connection of the Feet (Te Tuhono Tapu o ngā Waewae): The Cultural and Spiritual Impact of Diabetes-Related Lower Limb Amputation Among Māori. [PDF]

J Foot Ankle Res
Otene C, Ihaka B, Carroll MR.
europepmc   +1 more source

Assessing veterinary students’ attitudes towards pain in cattle before and after final‐year clinical training

Veterinary Record, EarlyView.
Abstract Background Cattle only show subtle signs of pain, making pain assessment difficult. The approach to pain and the use of analgesics depend on the treating person's experience and opinions. Methods Bavarian veterinary students were asked to answer two identical questionnaires before and after 12 weeks of clinical training in a ruminant clinic. A
Theresa Tschoner, Kristina R. Mueller, Yury Zablotski, Melanie Feist   +3 more
wiley   +1 more source

Single‐dose enflicoxib versus a 7‐day course of firocoxib for postoperative pain control in dogs undergoing orthopaedic surgery: A multicentre, randomised, masked, non‐inferiority study

Veterinary Record, EarlyView.
Abstract Background Perioperative analgesia is essential in dogs undergoing orthopaedic surgery, and enflicoxib's long duration makes single‐dose administration attractive. Methods A prospective, multicentre, randomised, masked trial compared enflicoxib (8 mg/kg) given 24 hours before surgery with firocoxib (5 mg/kg) given daily for 7 days. Two hundred
Marta Salichs, José I. Redondo, Anabel Blasco‐Moreno, Llorenç Badiella, Josep Homedes   +4 more
wiley   +1 more source

Targeted Muscle Reinnervation (TMR) or Regenerative Peripheral Nerve Interface (RPNI) for pain prevention in patients with limb amputation: A protocol for a systematic review and meta-analysis. [PDF]

PLoS One
Del Moral Preciado J, Gurpegui D, Royo M, Hontanilla B.   +3 more
europepmc   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

VIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro, Kellie Fortune, Eimear Daly, Luca McCann, Merhan Soltan, Seamus Sreenan, Fabio Quondamatteo   +6 more
wiley   +1 more source

Heme oxygenase 1 activity mediates red blood cell clearance and tail fin regeneration in zebrafish larvae. [PDF]

Sci Rep
Mirza A, Crawte S, Muñoz-Montecinos C, Mukherjee S, Lieschke GJ, Allende ML, Morales Castro RA.   +6 more
europepmc   +1 more source

Successful in situ replantation of fingertip amputation without vascular anastomosis: A case report. [PDF]

Medicine (Baltimore)
Sun P, Cai X, Wang X.
europepmc   +1 more source

Explosive Weapons Trauma Care Collective (EXTRACCT) Clinical Practice Guideline: Transfer of Critically Injured Casualties

World Journal of Surgery, EarlyView.
Blast‐injured patients often present to healthcare facilities which cannot definitively meet their clinical needs. This clinical practice guideline (CPG) reviews and describes best practice for inter‐facility transfer of casualties in resource limited and conflict‐afflicted contexts where there may not be a formal referral pathway or specialized inter ...
Emma Butterfield, Gavin Wooldridge, Solomon Abraha Asfaw, Mervat Alhilal, Mardi Steere, Benjamin W. Wachira, Paul Reavley, Roman Shtybel, Marius Rehn, On behalf of theEXTRACCT Clinical Practice Guidelines collaboration   +9 more
wiley   +1 more source

Functional Outcomes Following Amputation in Electrical Burn Injuries: A Prospective Observational Study Utilizing the Sickness Impact Profile (SIP) and International Classification of Impairments, Disabilities, and Handicaps (ICIDH) Frameworks. [PDF]

Cureus
Sankhla A, Sharma AK, Verma V.
europepmc   +1 more source