Results 61 to 70 of about 15,086 (227)

Retinoic Acid‐Related Orphan Nuclear Receptor Alpha Promotes Cartilage Degeneration in Osteoarthritis by Activating the Wnt/β‐Catenin Pathway

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
During the development of OA, elevated RORα in chondrocytes inhibits β‐catenin degradation in the cytoplasm by activating the Wnt/β‐catenin signaling pathway. When β‐catenin protein accumulates excessively in the cytoplasm, it is transferred to the nucleus and binds to the cytosolic TCF/LEF transcriptional complex, which activates downstream target ...
Ruijue Zhu, Tianwei He, Jiawei Di, Lang Mai, Depeng Wu, Mudan Huang, Yankui Liu, Zhongyu Liu, Liangming Zhang, Lei He   +9 more
wiley   +1 more source

Influence of physical capacities of males with transtibial amputation on gait adjustments on sloped surfaces [PDF]

, 2014
The aim of the study was to investigate how kinematic and kinetic adjustments between level and slope locomotion of persons with transtibial amputation are related to their individual muscular and functional capacities.
MARTINET, Noël, LANGLOIS, Karine, FODÉ, Pascale, VILLA, Coralie, BONNET, Xavier, LAVASTE, François, PILLET, Helene   +6 more
core   +1 more source

When Public Health Becomes the Weapon: Current and Prospective Consequences of the Genocide in Gaza

World Medical &Health Policy, Volume 18, Issue 2, June 2026.
ABSTRACT Catastrophic humanitarian conditions during the 2023–2025 genocide in Gaza have caused a public health crisis of exceptional magnitude. This article summarizes key short‐ and long‐term health consequences for Gaza's civilian population and outlines priorities for recovery.
Therese Alexandra Evald, Nanna Gram Ahlmark, Clara Barfod Parellada, Andreea Micula, Caroline Klint Johannesen, Dana Bdier, Fayez Mahamid, Hilde Lausund, Jane Brandt Sørensen, Maha Aon, Majd Qannita, Maren Johanne Heilskov Rytter, Nanna Maaløe, Nina Jøranson, Sara Aakre Faradonbeh, Vibeke Brix Christensen, Waseem Alzaanin, Sigurd Lauridsen, Helle Timm, Frederik Schou‐Juul   +19 more
wiley   +1 more source

Rehabilitation of bilateral lower extremity amputees [PDF]

, 1985
Impairments and disabilities of forty-two bilateral lower extremity amputees resistered at the Okayama Prefectural Rehabilitation Center from 1967 to 1983 were analysed. Sixty-nine percent of the amputation were related to trauma.
Toshihiro SUGIHARA, Sugihara, Toshihiro
core   +1 more source

Bilateral proprioceptive changes in athlete and non-athlete amputees with unilateral below-knee amputation

طب جانباز, 2014
Background & Purpose: The definitive loss of a body segment and its somatosensory afferents can profoundly affect the internal body representation, requiring adaptation to restore sensorimotor function. The purposes of the study were: (1) To compare knee
A.A. Norasteh, Z. Zarandy
doaj  

Modeling of a New Percutaneous Orthopedic Implant System to Control the Post-surgery Osseointegration Process [PDF]

Journal of Biomedical Physics and Engineering
This study presents a mechanical model of a novel medical device designed to optimize the osseointegration process in upper and lower limb amputees, leading to the promotion of optimal rehabilitation. The medical device is developed to reduce the risk of
Mohamed Faoussi, Salim Bounou, Mohammed Wahbi   +2 more
doaj   +1 more source

Digitizing Dignity: Analyzing Digital Twins Through the Lens of Multidimensional Human Dignity

Bioethics, Volume 40, Issue 5, Page 491-498, June 2026.
ABSTRACT In precision medicine, digital twins—virtual models of patients created using personalized data and advanced machine learning—are potentially changing healthcare by predicting health outcomes and guiding medical decisions. However, their use raises complex ethical questions, particularly concerning their relationship to human dignity. Patients
Andrew J. Barnhart
wiley   +1 more source

Diabetic foot ulcer‐related amputation is associated with twofold increased risk of cardiovascular disease: A Korean National Health Information Database Study

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 1024-1033, June 2026.
Data/Design: Nationwide, population‐based longitudinal cohort using the Korean National Health Insurance Service health checkup database (index 2009–2012) with follow‐up through December 31, 2018. Population/Exposure: Adults with diabetes (N = 1,229,689); DFU‐related amputation at baseline (n = 1,486) vs no DFU‐related amputation.
Jinsun Jang, Bong‐Seong Kim, Hye Won Yang, Heejun Son, Dong Yeon Lee, Min Gyu Kyung, Hwan Jun Jae, Saebeom Hur, Sang Wha Kim, Sanghyun Ahn, Kyung‐Do Han, Soo Heon Kwak   +11 more
wiley   +1 more source

The Development of a Myoelectric Training Tool for Above-Elbow Amputees

, 2012
The objective of above-elbow myoelectric prostheses is to reestablish the functionality of missing limbs and increase the quality of life of amputees. By using electromyography (EMG) electrodes attached to the surface of the skin, amputees are able to ...
Carey, Jason P., Fahimi, Farbod, Dawson, Michael R.   +2 more
core   +1 more source

تصور مقترح لتفعيل دور الاخصائي الاجتماعي في تحقيق المساندة الاجتماعية لجماعات مبتوري الأطراف [PDF]

مجلة مستقبل العلوم الإجتماعیة
استهدفت الدراسة الحالية تحديد الأدوار التي يقوم بها الأخصائي الاجتماعي لتحقيق المساندة الاجتماعية لمبتوري الأطراف وتحديد الممارسات التي يستخدمها الاخصائي الاجتماعي لتحقيق المساندة الاجتماعية لمبتوري الاطراف و المعوقات التي تواجه الاخصائي الاجتماعي في ...
إيمان فتحى إبراهيم علي
doaj   +1 more source