Results 151 to 160 of about 290,160 (299)

Radical Stability Paradox: Substituent Effects versus Heats of Formation

open access: yesChemistry – A European Journal, EarlyView.
Rethinking molecular stability: Quantum‐chemical analyses show that the greater stability of tertiary over primary organic radicals is not caused by stabilizing substituent effects but by the inherent stability of the substituent. ABSTRACT Recently, we have shown that alkyl substituents destabilize the carbon radical center of organic radicals. However,
Daniela Rodrigues Silva   +3 more
wiley   +1 more source

Corrigendum to 'Effect of a multidisciplinary lifestyle intervention on body composition in people with osteoarthritis: Secondary analysis of the "Plants for Joints" randomized controlled trial' [Osteoarthritis and Cartilage Open 6 (2024) 100524]. [PDF]

open access: yesOsteoarthr Cartil Open
Wagenaar CA   +10 more
europepmc   +1 more source

Breaking Barriers: Characterization of the Intradermal Lipopolysaccharide Challenge as an In Vivo Model for Controlled Induction of Vascular Leakage in Healthy Volunteers

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Vascular leakage and its associated phenomena vasodilation and endothelial activation are pathophysiological features of various diseases. Multiple drug candidates targeting these phenomena are in development, necessitating translational models to demonstrate proof‐of‐pharmacology and proof‐of‐mechanism in early‐phase clinical trials.
Marella Cornelia Elizabeth van Ruissen   +10 more
wiley   +1 more source

Corrigendum: National Early Warning Score for Predicting Clinical Outcome of Acute Pulmonary Embolism in Intermediate-High Risk Patients. [PDF]

open access: yesTH Open
Overgaauw AJC   +8 more
europepmc   +1 more source

Reducing the Burden of Interaction Studies in Cancer Patients Using a Stable Isotopically Labeled Microtracer: A Proof‐of‐Concept Study with Alectinib

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditional drug‐food interaction studies of oral anticancer agents have a high patient burden. A patient‐friendly alternative approach to studying food effects could be the use of stable isotopically labeled microtracers. A prospective, single‐center, open‐label, crossover, food effect study with the microtracer 2H6‐alectinib was conducted in patients
Ma Ida Mohmaed Ali   +9 more
wiley   +1 more source

Drawing cancer chronicles: A qualitative study to evaluate narrative meaning-making over time and in response to a meaning-centred care intervention. [PDF]

open access: yesPLoS One
Evans ERE   +18 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy