Results 171 to 180 of about 277,288 (290)

PFR AMSTERDAM 2022

open access: yesEuropean Journal of Volunteering and Community-Based Projects
Laura Marcia, Ludovica Rossi
doaj   +2 more sources

Faecal amino acids stability: investigating optimal sampling conditions for analysis. [PDF]

open access: yesMetabolomics
Opperman RCM   +5 more
europepmc   +1 more source

Effect of Mild to Moderate Hepatic Impairment on Valemetostat Pharmacokinetics: An Open‐Label, Phase I Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Valemetostat tosylate (valemetostat) is a dual inhibitor of enhancer of zeste homolog (EZH) 2 and EZH1, approved in Japan for the treatment of relapsed/refractory peripheral T‐cell lymphoma and adult T‐cell leukemia/lymphoma. This Phase I, open‐label study evaluated the pharmacokinetics and safety of a single 50‐mg oral dose of valemetostat in
Masaya Tachibana   +8 more
wiley   +1 more source

Longitudinal associations between amyloid and symptoms of depression and anxiety in subjective cognitive decline: the impact of personality characteristics. [PDF]

open access: yesFront Psychiatry
Trieu C   +10 more
europepmc   +1 more source

A Base‐Mediated Rearrangement of the Benzylic 1,5‐Hexadipyridynyl Moiety

open access: yesChemPlusChem, Accepted Article.
We report a previously unrecognized base‐mediated rearrangement of a benzylic 1,5‐hexadipyridynyl moiety. Upon exposure to base, we show this structural motif to rearrange into a constrained vinyl‐pyridine substituted cyclobutene. Computational modeling indicates that the rearrangement takes place following a route involving stepwise deprotonation ...
Wouter A. Remmerswaal   +8 more
wiley   +1 more source

Molecular Classification of Resected Primary Duodenal Adenocarcinoma. [PDF]

open access: yesGenes Chromosomes Cancer
de Bakker J   +9 more
europepmc   +1 more source

Implementing Pre‐Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
In pediatric oncology, pharmacogenetic guidelines are underutilized and the potential impact of pre‐emptive pharmacogenetic screening remains largely unexplored despite this field's need for individualized approaches. While comprehensive pharmacogenetic guidelines are not yet available for all anticancer drugs, evidence‐based recommendations exist for ...
Emma C. Bernsen   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy